Purpose Of Review: To review recent studies that may help to identify patients in the ICU who benefit from nutrition support.
Recent Findings: One recent controlled trial did not show any clinical benefit of nutrition support among a sample of ICU patients who were hitherto believed to benefit from nutrition support. Several recent observational studies suggest benefit of nutrition support among patients who have a high nutric score, in itself derived from an observational study.
Summary: Regrettably, the decision about nutrition support in ICU patients still depends on physiological reasoning: a high degree of inflammation/stress metabolism, which will last for a considerable time, especially among those who are fragile (already malnourished, elderly, those with chronic diseases and/or other comorbidities).
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http://dx.doi.org/10.1097/MCO.0000000000000551 | DOI Listing |
BMJ Nutr Prev Health
July 2024
National University of Singapore, Singapore.
The health and economic benefits of breastfeeding for mothers, infants and the broader community are well established; however, breastfeeding rates remain suboptimal in Singapore. This commentary reviews the journey Singapore, a high-income and well-resourced country, has taken over the past two decades to promote breastfeeding. We discuss where we are currently at, the measures implemented to achieve our targets and next steps ahead.
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August 2024
Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
Background: Subjects with metabolic syndrome and obesity have higher levels of inflammation with depression of the vitamin D (VD) hydroxylase/metabolising genes () required to convert VD consumed in the diet into 25(OH)VD. Compared with total 25(OH)VD levels, measurement of bioavailable 25(OH)VD is a better method to determine the beneficial effect of VD.
Objective: This study investigates whether cosupplementation with VD and L-cysteine (LC), which downregulates inflammation and upregulates VD-regulating genes, provides a better therapeutic benefit than supplementation with VD-alone in African Americans (AA).
BMJ Nutr Prev Health
August 2024
Department of Nutrition, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas, USA.
This article continues from a prior commentary on evaluating the risk of bias in randomised controlled trials addressing nutritional interventions. Having provided a synopsis of the risk of bias issues, we now address how to understand trial results, including the interpretation of best estimates of effect and the corresponding precision (eg, 95% CIs), as well as the applicability of the evidence to patients based on their unique circumstances (eg, patients' values and preferences when trading off potential desirable and undesirable health outcomes and indicators (eg, cholesterol), and the potential burden and cost of an intervention). Authors can express the estimates of effect for health outcomes and indicators in relative terms (relative risks, relative risk reductions, OR or HRs)-measures that are generally consistent across populations-and absolute terms (risk differences)-measures that are more intuitive to clinicians and patients.
View Article and Find Full Text PDFBMJ Nutr Prev Health
December 2024
Laboratory of Toxicology and Forensic Sciences, Medical School of the University of Crete, Crete, Greece.
Background: Non-communicable diseases (NCDs), known as chronic diseases, significantly impact patients' quality of life (QoL) and increase medical expenses. The majority of risk factors are modifiable, and metabolomics has been suggested as a promising strategy for their evaluation, though real-world data are scarce. This study evaluated the QoL improvement and cost-effectiveness of a metabolomics-based treatment for NCDs, aiming to restore metabolic dysfunctions and nutritional deficiencies.
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January 2025
Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, United States.
Introduction: Nutrition during pregnancy significantly impacts maternal and birth outcomes. A key factor contributing to the rise in adverse maternal and birth outcomes is poor nutrition. Produce prescription programs have the potential to address pregnancy-related adverse outcomes such as hypertensive disorders and gestational diabetes, but scientific evidence is limited.
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