is a medicinal species of the Brazilian Cerrado. The extract and fractions of this plant were analysed by LC-DAD-MS. Identified constituents included glycosylated and non-glycosylated flavonoids, especially quercetin, and phenylpropanoids, such as chlorogenic acids. The antioxidant activity was significantly more pronounced for the methanol extract and fractions than that of the commercial antioxidant 2,6-di-tert-butyl-4-methylphenol (BHT). Maximum larvicidal activity of 85.83% was recorded in the dichloromethane fraction (LC = 469.78 µg mL). The methanol extract and fractions presented low toxicity to larvae of the shrimp brine indicating selectivity for . These results contribute to the phytochemical study of . These compounds were identified for the first time in this species and encourage additional work on the isolation of compounds present in the extract and fractions of to evaluate the possibility of using them as natural sources of antioxidants, since cytotoxic effects were not demonstrated.
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http://dx.doi.org/10.1080/14786419.2018.1543678 | DOI Listing |
ACS Omega
December 2024
Laboratory of Bioactive Natural Products, Department of Biochemistry, Institute of Biological Science, Federal University of Juiz de Fora, Juiz de Fora, MG 36036-900, Brazil.
is a plant widely cultivated for food and medicinal purposes. species have been reported as anti-inflammatory, antibacterial, anxiolytic, and antinephritic agents. This study aimed to evaluate the anti-inflammatory potential of the ethanolic extract (EE) from the aerial parts of and its most promising fraction in models of acute and chronic inflammation, including a psoriasis-like mouse model.
View Article and Find Full Text PDFCapillary zone electrophoresis (CZE) is gaining attention in the field of single-cell proteomics for its ultra-low-flow and high-resolution separation abilities. Even more sample-limited yet rich in biological information are phosphoproteomics experiments, as the phosphoproteome composes only a fraction of the whole cellular proteome. Rapid analysis, high sensitivity, and maximization of sample utilization are paramount for single-cell analysis.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
December 2024
Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Background And Aims: The objective of this study was to assess the associations of birth weight with cardiac structure and function in adults with dextro-transposition of the great arteries (D-TGA) who underwent the arterial switch operation (ASO).
Methods And Results: Thirty-nine ASO patients (age 24.4 ± 3.
PeerJ
December 2024
Department of Oral & Craniofacial Sciences, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur, Malaysia.
Background: is widely recognised as a periodontal pathogen. In recent years, there has been growing interest in the use of medicinal plant extracts as alternative treatments for periodontitis to combat the emergence of antibiotic-resistant bacteria. L.
View Article and Find Full Text PDFCureus
November 2024
Internal Medicine, Hamad Medical Corporation, Doha, QAT.
Background Diabetic nephropathy is a serious complication of diabetes that significantly increases the risk of chronic kidney disease (CKD) and end-stage renal disease (ESRD). A critical concern in managing patients with diabetic nephropathy is the prevalence of potentially inappropriate medications (PIMs), which can exacerbate kidney dysfunction and lead to adverse health outcomes. PIMs are defined as medications whose risks outweigh their benefits, particularly when safer alternatives are available.
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