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Aim: Basic self disturbance is a putative core vulnerability marker of schizophrenia spectrum disorders. The primary aims of the Self, Neuroscience and Psychosis (SNAP) study are to: (1) empirically test a previously described neurophenomenological self-disturbance model of psychosis by examining the relationship between specific clinical, neurocognitive, and neurophysiological variables in UHR patients, and (2) develop a prediction model using these neurophenomenological disturbances for persistence or deterioration of UHR symptoms at 12-month follow-up.

Methods: SNAP is a longitudinal observational study.

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Imagery-Mediated Verbal Learning Depends on Vividness-Familiarity Interactions: The Possible Role of Dualistic Resting State Network Activity Interference.

Brain Sci

June 2019

Neuroscience of Imagination Cognition and Emotion Research (NICER) Lab, Neuroscience Department, Carleton University, Ottawa, ON K1S 5B6, Canada.

Article Synopsis
  • - The study analyzed how noun-cues' familiarity and imagery vividness affect verbal learning, focusing on their impact on the recall of nouns and reaction times during retrieval.
  • - Results showed that noun-cues with matching levels of vividness and familiarity led to better recall, while mismatched cues resulted in the lowest recall probabilities and slower reaction times.
  • - The findings challenge existing memory theories and suggest a dualistic neuropsychological model, indicating that competition and synergy between two brain networks (DMN and TPN) influence long-term memory consolidation and could help identify memory deficits in various psychological disorders.
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Mindfulness-induced selflessness: a MEG neurophenomenological study.

Front Hum Neurosci

September 2013

The Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Bar-Ilan University Ramat Gan, Israel.

Contemporary philosophical and neurocognitive studies of the self have dissociated two distinct types of self-awareness: a "narrative" self-awareness (NS) weaving together episodic memory, future planning and self-evaluation into a coherent self-narrative and identity, and a "minimal" self-awareness (MS) focused on present momentary experience and closely tied to the sense of agency and ownership. Long-term Buddhist meditation practice aims at realization of a "selfless" mode of awareness (SL), where identification with a static sense of self is replaced by identification with the phenomenon of experiencing itself. NS-mediating mechanisms have been explored by neuroimaging, mainly fMRI, implicating prefrontal midline structures, but MS processes are not well characterized and SL even less so.

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Introduction: After a hypnotic induction, medium and highly hypnotizable individuals often report spontaneous alterations in various dimensions of consciousness. Few studies investigating these experiences have controlled for the inherent demands of specific hypnotic suggestions and fewer still have considered their dynamic properties and neural correlates.

Methods: We adopted a neurophenomenological approach to investigate neutral hypnosis, which involves no specific suggestion other than to go into hypnosis, with 37 individuals of high, medium, and low hypnotizability (Highs, Mediums, and Lows).

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