Synthesis of psammaplin A analogues is described. Screening for antibiofilm activity of the targeted library afford some interesting elements in terms of structure-activity relationships. Some compounds exhibited EC50 in the range of ampicillin against three strains of gramnegative bacteria without toxic effect.
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| http://dx.doi.org/10.1016/j.bmcl.2018.12.047 | DOI Listing |
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