Fabrication and characterization of different surface charged cellulose electrospun scaffolds including cellulose acetate (CA), cellulose, carboxymethyl cellulose (CMC) and quaternary ammonium cationic cellulose (QACC) for biomedical applications have been reported in this research. Several instrumental techniques were employed to characterize the nanofibers. MTT assay and cell attachment studies were also carried out to determine the cytocompatibility, viability and proliferation of the scaffolds. Fabricated CA, cellulose, CMC and QACC nanofibers had 100-600 nm diameter, -9, -1.75, -12.8, + 22 mV surface potential, 2.5, 4.2, 7.2, 7 MPa tensile strength, 122, 320, 515, 482 MPa Young modules, 430, 530, 670 and 642% water uptake and 92°, 58°, 45°, 47° contact angle respectively. The findings showed that cell adhesion and proliferation is strongly enhanced on the modified surfaces with quaternary ammonium and carboxymethyl groups. We believe the use of cationic and anionic surface modified cellulose electrospun nanofibers presents promising materials for biomedical applications.
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http://dx.doi.org/10.1016/j.carbpol.2018.12.028 | DOI Listing |
Int J Biol Macromol
January 2025
Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Although tissue engineering science has made great progress, wound healing has remained a significant clinical challenge, especially in cases of severe injuries requiring advanced treatment strategies. This study aimed to develop patient-friendly in situ gelling nanofibers composed of oxidized carboxymethyl cellulose (OCMC) and gelatin for wound healing applications. A two-axial electrospinning technique was employed to fabricate OCMC/PVA-Gelatin hybrid nanofibers.
View Article and Find Full Text PDFPest Manag Sci
January 2025
College of Plant Protection, Shanxi Agricultural University, Taigu, China.
Background: As sex pheromones are environmentally friendly and specific, they are often used to monitor and control oriental fruit moths (OFMs). Currently, non-biodegradable polymers are commonly employed as carriers to prepare controlled sex pheromone release systems for plant protection. Electrospinning is a relatively simple technique for preparing biodegradable nanofibers that allows for the controlled release of sex pheromones.
View Article and Find Full Text PDFMacromol Rapid Commun
January 2025
UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London, WC1N 1AX, UK.
Antimicrobial resistance poses a growing threat to public health globally. Multidrug resistant Pseudomonas (P.) aeruginosa is detected in many infected wounds and is very challenging to treat with antibiotics.
View Article and Find Full Text PDFMacromol Biosci
January 2025
Institute for Technical Chemistry, Macromolecular Chemistry, TU Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.
Implant-integrated drug delivery systems that enable the release of biologically active factors can be part of an in situ tissue engineering approach to restore biological function. Implants can be functionalized with drug-loaded nanoparticles through a layer-by-layer assembly. Such coatings can release biologically active levels of growth factors.
View Article and Find Full Text PDFACS Nano
January 2025
School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Republic of Singapore.
Hydrogel-based sensors have been widely studied for perceiving the environment. However, the simplest type of resistive sensors still lacks sensitivity to localized strain and other extractable data. Enhancing their sensitivity and expanding their functionality to perceive multiple stimuli simultaneously are highly beneficial yet require optimal material design and proper testing methods.
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