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Exosomes derived from bone marrow mesenchymal stem cells ameliorate chemotherapeutically induced damage in rats' parotid salivary gland.
Oral Maxillofac Surg
January 2025
Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Objective: A nanometer-sized vesicles originating from bone marrow mesenchymal stem cells (BMMSCs), called exosomes, have been extensively recognized. This study defines the impact of BMMSCs and their derived exosomes on proliferation, apoptosis and oxidative stress (OS) levels of CP-induced parotid salivary gland damage.
Methods: BMMSCs were isolated from the tibia of four white albino rats and further characterized by flowcytometric analysis.
Effects of 3-day fasting on secretory IgA concentration in the saliva and lymphotoxin alpha expression in healthy volunteers: a proof of concept study.
Nutr Hosp
December 2024
Clinical Nutrition Service. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán.
Background: animal studies have shown that enteral stimuli play an important role in modulating gut-associated lymphoid tissue.
Objective: the main objectives of this study were 1) to evaluate the effect of 3-day fasting on secretory immunoglobulin A (S-IgA) in parotid saliva and 2) to determine the levels of lymphotoxin (LT) transcription in peripheral blood mononuclear cells (PBMNC) from healthy volunteers as a proxy for studying GALT health.
Methods: these adult volunteers had fasted for three days as part of a cultural ritual.
Treatment course of cavitary pulmonary tuberculosis combined with tuberculosis in a parotid Warthin's tumor: a case report and literature review.
BMC Infect Dis
November 2024
Department of Pathology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, 570311, China.
Background: Extrapulmonary tuberculosis (TB) is a relatively rare form of tuberculosis infection, accounting for approximately 15% of all tuberculosis infections. Lymph nodes are the most commonly affected sites, while involvement of the parotid gland is extremely rare.
Case Presentation: We present the case of a 65-year-old male patient with a one-month history of a left parotid mass.
Tempol mitigates inflammation, oxidative stress, and histopathological alterations of cadmium-induced parotid gland injury in rats.
Life Sci
December 2024
Anatomy and Embryology Department, Faculty of Medicine, Tanta University, Tanta 31511, Egypt; Public Health Department, College of Applied Medical Sciences, King Faisal University, P.O. Box 400, AlAhsa 31982, Saudi Arabia.
Unlabelled: Cadmium (Cd) is a potent environmental pollutant that causes functional and structural damage to the salivary glands. Tempol (TEM) has powerful antioxidant activity that can potentially preserve organ function.
Aims: This study was designed to investigate the protective effects of TEM on Cd-induced toxicity in rat parotid salivary glands.
A Case of Stress-Induced Cardiomyopathy After Ketamine Infusion.
Cureus
May 2024
Cardiovascular Medicine, University of Utah Health, Salt Lake City, USA.
Article Synopsis
- A 64-year-old woman with hypothyroidism and parotid sarcoidosis experienced sudden chest pain and shortness of breath.
- An echocardiogram showed a temporary drop in heart function, indicating stress-induced cardiomyopathy, with no blockage found in her coronary arteries.
- The patient's recent ketamine infusion for mental health issues might have triggered her cardiac symptoms, highlighting the need for caution when using ketamine in patients with heart conditions and the necessity for more research on its cardiovascular effects.
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