Application of controlled release urea (CRU) is recommended to reduce the undesirable environmental effects resulting from urea application. However, the overall effects of CRU on maize productivity and reactive nitrogen (N) losses remain unclear. Our global meta-analysis based on 866 observations of 120 studies indicated that application of CRU instead of urea (same N rate) increased maize yield by 5.3% and nitrogen use efficiency (NUE) by 24.1%, and significantly decreased nitrous oxide (NO) emission, N leaching and ammonia (NH) volatilization by 23.8%, 27.1% and 39.4%, respectively. The increase of NUE and reduction of NO emission by CRU application were greater with medium and high N rates (150 ≤ N < 200 and N ≥ 200 kg N ha) than with low N rates. The reduction in NO emission and N leaching with CRU application were enhanced when soil organic carbon (SOC) content was <15.0 g kg, and soil texture was medium or coarse. The reduction in NO emission and NH volatilization with CRU were greater in soils with pH ≥ 6.0. We concluded that use of CRU should be encouraged for maize production, especially on light-textured soils with low organic matter content.
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http://dx.doi.org/10.1016/j.envpol.2018.12.059 | DOI Listing |
J Biomater Sci Polym Ed
January 2025
School of Studies in Pharmaceutical Sciences, Jiwaji University, Gwalior, India.
Ulcerative colitis, a chronic inflammatory condition of the colon, requires precise and targeted treatment, and polysaccharides, with their pH responsiveness and biodegradability, offer an innovative approach for colon-specific drug delivery. This study aims to develop a highly precise drug delivery system with enhanced therapeutic and targeting efficiency for ulcerative colitis, focusing on the preparation, optimisation, and evaluation of dual cross-linked mesalamine-loaded sericin-pectin (DSPs) micro-beads. These beads utilise the pH-responsive and microflora biodegradability properties of polysaccharides for targeted colon delivery, employing the Response Surface Methodology.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Center for Protein Studies, Faculty of Biology, University of Havana (UH), 25(th) Street, corner to J Street. Square of Revolution, Havana 10400. Cuba; NanoCancer, Molecular Immunology Center (CIM), 216 Street, corner to 15 Street, Playa, Havana 11600, Cuba. Electronic address:
Gene expression manipulation is pivotal in therapeutic approaches for various diseases. Non-viral delivery systems present a safer alternative to viral vectors, with reduced immunogenicity and toxicity. However, their effectiveness in promoting endosomal escape, a crucial step in gene transfer, remains limited.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Université Paris Est Creteil, CNRS, Institut Chimie et Matériaux Paris Est, UMR 7182, 2 Rue Henri Dunant, 94320 Thiais, France. Electronic address:
In the present investigation, redox-responsive-based dextran carriers were developed for the controlled release of hydrophobic molecules via a reducing agent naturally present in cells, namely glutathione. In this sense, dextran was modified with a thiol derivative. The roles of the hydrophilic segments in the molecular self-organisation of polysaccharide derivatives into nanoparticles were investigated by varying the average dextran molar mass.
View Article and Find Full Text PDFSci Total Environ
January 2025
Sarawak Tropical Peat Research Institute, Kota Samarahan, Malaysia.
Tropical peatlands are significant sources of methane (CH₄), but their contribution to the global CH₄ budget remains poorly quantified due to the lack of long-term, continuous and high-frequency flux measurements. To address this gap, we measured net ecosystem CH exchange (NEE-CH) using eddy covariance technique throughout the conversion of a tropical peat swamp forest to an oil palm plantation. This encompassed the periods before, during and after conversion periods from 2014 to 2020, during which substantial environmental shifts were observed.
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