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http://dx.doi.org/10.1136/gutjnl-2018-317839DOI Listing

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Follow-on RifAximin for the Prevention of recurrence following standard treatment of Infection with (RAPID): a randomised placebo controlled trial.

Gut

July 2019

Nottingham Digestive Diseases Centre and NIHR Nottingham Biomedical Research Centre at Nottingham University Hospitals NHS Trust, the University of Nottingham, Nottingham, Notts, UK.

Background: Clostridium difficile infection (CDI) recurs after initial treatment in approximately one in four patients. A single-centre pilot study suggested that this could be reduced using 'follow-on' rifaximin treatment. We aimed to assess the efficacy of rifaximin treatment in preventing recurrence.

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