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Harvey Cushing: France Military Hospital Surgical Unit Head and World War I U.S. Army Medical Corps Commissioner.
World Neurosurg
January 2025
Department of Neurosurgery, New York University Grossman School of Medicine, New York City, New York City, USA.
Background: This historical account reviews the course and lasting impact of Dr. Harvey Cushing (1869-1939) in neurosurgery.
Methods: The writing of this project was sparked by the discovery of original scientific and bibliographical information about Cushing.
A systematic review of the role of systemic inflammation-based prognostic scores in patients with abdominal aortic aneurysm.
Surgeon
August 2024
New Lister Building, University of Glasgow, Glasgow, United Kingdom.
Background And Aims: Activation of the systemic inflammatory response (SIR) is associated with inferior outcomes across a spectrum of disease. Routinely available measures of the SIR (neutrophil:lymphocyte ratio (NLR), platelet:lymphocyte ratio (PLR), systemic immune-inflammatory index (SII), systemic inflammatory grade (SIG)) have been shown to provide prognostic value in patients undergoing surgical intervention. The present study aimed to review the literature describing the prognostic association of NLR, PLR, SII and SIG in patients undergoing intervention for abdominal aortic aneurysm (AAA).
View Article and Find Full Text PDFInhibitors of the small membrane (M) protein viroporin prevent Zika virus infection.
Elife
August 2024
Astbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
, including (ZIKV), are a significant global health concern, yet no licensed antivirals exist to treat disease. The small membrane (M) protein plays well-defined roles during viral egress and remains within virion membranes following release and maturation. However, it is unclear whether M plays a functional role in this setting.
View Article and Find Full Text PDFImplementing a Clinical Pathway for Needs Assessment and Supportive Care Interventions.
JCO Oncol Pract
September 2024
Australian Cancer Survivorship Centre, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Despite advances in clinical cancer care, cancer survivors frequently report a range of persisting issues, unmet needs, and concerns that limit their ability to participate in life roles and reduce quality of life. Needs assessment is recognized as an important component of cancer care delivery, ideally beginning during active treatment to connect patients with supportive services that address these issues in a timely manner. Despite the recognized importance of this process, many health care systems have struggled to implement a feasible and sustainable needs assessment and management system.
View Article and Find Full Text PDFRobotic-assisted surgery for left-sided colon and rectal resections is associated with reduction in the postoperative surgical stress response and improved short-term outcomes: a cohort study.
Surg Endosc
May 2024
Academic Unit of Surgery and School of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, New Lister Building, Glasgow Royal Infirmary, Glasgow, G31 2ER, UK.
Introduction: There is growing evidence that the use of robotic-assisted surgery (RAS) in colorectal cancer resections is associated with improved short-term outcomes when compared to laparoscopic surgery (LS) or open surgery (OS), possibly through a reduced systemic inflammatory response (SIR). Serum C-reactive protein (CRP) is a sensitive SIR biomarker and its utility in the early identification of post-operative complications has been validated in a variety of surgical procedures. There remains a paucity of studies characterising post-operative SIR in RAS.
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