The case report presents the successful performance of laparoscopic cholecystectomy for situs viscerum inversus totalis in a female patient with chronic cholecystitis and cholecystolithiasis and summarizes current knowledge and approaches to this issue. Gallbladder empyema was found perioperatively, which has only been published once in a similar case before. Laparoscopic cholecystectomy in situs viscerum inversus totalis is a safe method to remove the gallbladder. Key words: situs viscerum inversus totalis laparoscopic cholecystectomy gallblader empyema.
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