The current marketing landscape, apart from conventional approaches, consists of campaigns designed especially for launching information diffusion processes within online networks. Associated research is focused on information propagation models, campaign initialization strategies and factors affecting campaign dynamics. In terms of algorithms and performance evaluation, the final coverage represented by the fraction of activated nodes within a target network is usually used. It is not necessarily consistent with the real marketing campaigns using various characteristics and parameters related to coverage, costs, behavioral patterns and time factors for overall evaluation. This paper presents assumptions for a decision support system for multi-criteria campaign planning and evaluation with inputs from agent-based simulations. The results, which are delivered from a simulation model based on synthetic networks in a form of decision scenarios, are verified within a real network. Last, but not least, the study proposes a multi-objective campaign evaluation framework with several campaign evaluation metrics integrated. The results showed that the recommendations generated with the use of synthetic networks applied to real networks delivered results according to the decision makers' expectation in terms of the used evaluation criteria. Apart from practical applications, the proposed multi-objective approach creates new evaluation possibilities for theoretical studies focused on information spreading processes within complex networks.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307867 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209372 | PLOS |
Disabil Rehabil
December 2024
Amsterdam UMC location University of Amsterdam, Public and Occupational Health, Amsterdam, The Netherlands.
Purpose: To explore the experiences of long-term sick-listed employees and those of employers with communication and collaboration during sick leave and the return-to-work (RTW) process.
Methods: Previously long-term sick-listed employees ( = 9) and employers ( = 9) were interviewed about their experiences with communication and collaboration during sick leave and RTW. Thematic analysis, utilizing patient journey mapping was applied to analyze and map out their experiences.
J Am Med Inform Assoc
December 2024
AI for Health Institute, Washington University in St Louis, St Louis, MO 63130, United States.
Objective: Early detection of surgical complications allows for timely therapy and proactive risk mitigation. Machine learning (ML) can be leveraged to identify and predict patient risks for postoperative complications. We developed and validated the effectiveness of predicting postoperative complications using a novel surgical Variational Autoencoder (surgVAE) that uncovers intrinsic patterns via cross-task and cross-cohort presentation learning.
View Article and Find Full Text PDFBiometrics
October 2024
RAND Corporation, Pittsburgh, PA 15213, United States.
Health care decisions are increasingly informed by clinical decision support algorithms, but these algorithms may perpetuate or increase racial and ethnic disparities in access to and quality of health care. Further complicating the problem, clinical data often have missing or poor quality racial and ethnic information, which can lead to misleading assessments of algorithmic bias. We present novel statistical methods that allow for the use of probabilities of racial/ethnic group membership in assessments of algorithm performance and quantify the statistical bias that results from error in these imputed group probabilities.
View Article and Find Full Text PDFClin Pharmacol Ther
December 2024
Flatiron Health, New York, NY, USA.
Clinical research has historically failed to include representative levels of historically underrepresented populations and these inequities continue to persist. Ensuring representativeness in clinical trials is crucial for patients to receive clinically appropriate treatment and have equitable access to novel therapies; enhancing the generalizability of study results; and reducing the need for post-marketing commitments focused on underrepresented groups. As demonstrated by recent legislation and guidance documents, regulatory agencies have shown an increased interest in understanding how novel therapies will impact the patient population that will receive them.
View Article and Find Full Text PDFOrphanet J Rare Dis
December 2024
Department of Internal Medicine D, and Interdisciplinary Fabry Center (IFAZ), University Hospital Muenster, Muenster, Germany.
Background: The aim of our multicenter study was to investigate the implementation of the European Fabry guidelines on therapeutic recommendations in female patients with Fabry disease (FD) and to analyze the impact of enzyme replacement therapy (ERT) in treated and untreated females.
Results: Data from 3 consecutive visits of 159 female FD patients from 6 Fabry centers were retrospectively analyzed. According to their treatment, patients were separated in 3 groups (untreated, n = 71; newly ERT-treated, n = 47; long-term ERT-treated, n = 41).
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