Vitamin D Deficiency as a Factor Influencing Asthma Control in Children.

Indian Pediatr

Department of Pediatrics, Sri Ramachandra Medical College and Research Institute, Chennai, India. Correspondence to: Dr Padmasani Venkat Ramanan, Professor, Department of Pediatrics, Sri Ramachandra Medical College and Research Institute, Chennai 600 116, India.

Published: November 2018

Objective: To study the association between asthma control and serum 25OH Vitamin D levels in children with moderate persistent asthma on preventer therapy.

Methods: Children aged 6-18 years, with moderate persistent asthma, on preventer therapy for ≥2 months were included. Control was categorized as good, partial or poor as per GINA guidelines. Serum 25 (OH) Vitamin D levels were measured and their relationship with the level of control was studied.

Results: Out of 50 children enrolled, 22 had well-controlled asthma, and 21 had partially controlled asthma. Vitamin D was deficient in 30 children and insufficient in 18 children. Children with vitamin D deficiency had significantly less well-controlled asthma as compared to those with insufficient or sufficient levels of 25 (OH) vitamin D (13.3% vs 88.9% vs 100%).

Conclusions: Vitamin D deficiency is associated with suboptimal asthma control.

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