A suppurative thyroiditis and perineal subcutaneous abscess related with aspergillus fumigatus: a case report and literature review.

BMC Infect Dis

Department of Critical Care Medicine, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, People's Republic of China.

Published: December 2018

AI Article Synopsis

  • Invasive aspergillosis is a serious condition primarily affecting immunocompromised patients, particularly those with hematological issues, and while the thyroid is usually resistant to infections, rare cases of aspergillosis have been reported.
  • A new case of aspergillus infection in the thyroid gland and nearby tissues was documented in a patient undergoing long-term glucocorticoid therapy for systemic lupus erythematosus, adding to the understanding of such rare occurrences.
  • The study reviewed 36 articles summarizing 41 similar cases of aspergillus infections, focusing on 29 cases diagnosed with aspergillus thyroiditis to inform clinical practices and patient outcomes.

Article Abstract

Background: Invasive aspergillosis is a complication in immunocompromised patients and commonly detected in patients with hematological malignancies, which mostly affect the lungs. Because of its high iodine content, rich blood supply and capsule, the thyroid is considered to be less prone to microbial invasion thus most infectious thyroiditis cases are caused by bacteria. However, a few case reports have described thyroid gland aspergilloses, most of which were due to disseminated invasive aspergillosis.

Case Presentation: We first report a case of thyroid gland and subcutaneous labium majus aspergillosis in a Chinese patient who received long-term glucocorticoid treatment for systemic lupus erythematosus (SLE) and lupus nephritis, and then we reviewed 36 articles describing similar aspergillus infections in 41 patients.

Conclusion: We included 29 cases of diagnosed aspergillus thyroiditis and analyzed clinical findings, treatments and outcomes to provide clinical information for diagnosis and prognosis of thyroiditis caused by Aspergillus fumigatus.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307113PMC
http://dx.doi.org/10.1186/s12879-018-3617-4DOI Listing

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