Purpose Of Review: Robotic-assisted laparoscopic retroperitoneal lymph node dissection (R-RPLND) is gaining acceptance as an alternative to open and laparoscopic RPLND for the treatment of testicular cancer. We discuss the current state of R-RPLND and summarize the latest relevant literature regarding the feasibility of this operation.
Recent Findings: R-RPLND has been utilized effectively for both treatment of high-risk, clinical stage I testicular cancer as well as in the postchemotherapy setting. The feasibility of R-RPLND has been established with complication rates comparable to open RPLND and with decreased postoperative hospital stay and blood loss.
Summary: As R-RPLND continues to evolve and experience grows in high-volume centers, more information will be gained regarding long-term oncologic outcomes. Ultimately, head-to-head trials comparing R-RPLND to open RPLND will be needed to determine the role of R-RPLND in the treatment of testicular cancer.
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http://dx.doi.org/10.1097/MOU.0000000000000582 | DOI Listing |
Alzheimers Dement
December 2024
Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Background: The risk of cognitive decline in cancer survivors may be increased by platinum-based chemotherapy. Evidence indicates that physical exercise has a potential to reduce chemotherapy-related toxicity. The aim of this study was to assess effects of a 6-month aerobic-strength training on cognitive functions, metabolic flexibility, anthropometric parameters and physical fitness in testicular germ cell tumor (TGCT) survivors, treated with platinum-based chemotherapy.
View Article and Find Full Text PDFArab J Urol
September 2024
Department of Urology, Hamad Medical Corporation, Doha, Qatar.
Objective: To evaluate the effects of age on semen and hormonal parameters following microsurgical varicocelectomy among patients with grade 3 varicocele, and to compare fertility outcomes between younger (<40 years) and older (≥40 years) men.
Methods: Retrospective cohort study of infertile patients with clinical left grade 3 varicocele who underwent microsurgical subinguinal varicocelectomy (MV). Patients meeting the inclusion criteria ( = 550) were divided into two groups based on their age at the time of MV: <40 ( = 441) and ≥40 years ( = 109).
Public Health Nurs
January 2025
Faculty of Health Sciences, Department of Nursing, Eastern Mediterranean University, Famagusta, North Cyprus, Turkey.
Objectives: The aim of this study was to determine the effects of a training program based on educational brochures and audio recordings of testicular cancer (TC) stories on testicular self-examination (TSE) and health beliefs among university students.
Design: The study had a pretest-posttest, control group experimental design.
Sample: This study was conducted with 106 students in Turkey.
J Clin Med
December 2024
Department of Urology, University Hospital, LMU Munich, 81377 Munich, Germany.
Contrast-enhanced ultrasound (CEUS) is a promising modality for differentiating benign and malignant lesions in various organs, including the testis. Testicular tumors, common in young men, are often treated with radical orchiectomy, which can have significant consequences. This study aimed to analyze CEUS parameters and their association with malignant testicular tumors.
View Article and Find Full Text PDFGenes (Basel)
December 2024
Department of Biochemistry & Biotechnology, School of Health Sciences, University of Thessaly, 41335 Larissa, Greece.
Background/objectives: Testicular germ cell tumors (TGCT) are common in young adult men and have high cure rates. Conventional serum tumor markers and imaging are not able to differentiate between histologic subtypes of the disease, which portend different prognoses and require distinct therapeutic strategies. Micro-RNAs (miRNAs) are small non-coding transcripts involved in the post-transcriptional regulation of gene expression, which have emerged as promising biomarkers in a variety of tumors.
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