Objectives: The Centers for Medicare and Medicaid Services requires hospitals to report compliance with a sepsis treatment bundle as part of its Inpatient Quality Reporting Program. We used recently released data from this program to characterize national performance on the sepsis measure, known as SEP-1.
Design: Cross-sectional study of United States hospitals participating in the Centers for Medicare and Medicaid Services Hospital Inpatient Quality Reporting Program linked to Centers for Medicare and Medicaid Services' Healthcare Cost Reporting Information System.
Setting: General, short-stay, acute-care hospitals in the United States.
Measurements And Main Results: We examined the hospital factors associated with reporting SEP-1 data, the hospital factors associated with performance on the SEP-1 measure, and the relationship between SEP-1 performance and performance on other quality measures related to time-sensitive medical conditions. A total of 3,283 hospitals were eligible for the analysis, of which 2,851 (86.8%) reported SEP-1 performance data. SEP-1 reporting was more common in larger, nonprofit hospitals. The most common reason for nonreporting was an inadequate case volume. Among hospitals reporting SEP-1 performance data, overall bundle compliance was generally low, but it varied widely across hospitals (mean and SD: 48.9% ± 19.4%). Compared with hospitals with worse SEP-1 performance, hospitals with better SEP-1 performance tended to be smaller, for-profit, nonteaching, and with intermediate-sized ICUs. Better hospital performance on SEP-1 was associated with higher rates of timely head CT interpretation for stroke patients (rho = 0.16; p < 0.001), more frequent aspirin administration for patients with chest pain or heart attacks (rho = 0.24; p < 0.001) and shorter median time to electrocardiogram for patients with chest pain (rho = -0.12; p < 0.001).
Conclusions: The majority of eligible hospitals reported SEP-1 data, and overall bundle compliance was highly variable. SEP-1 performance was associated with structural hospital characteristics and performance on other measures of hospital quality, providing preliminary support for SEP-1 performance as a marker of timely hospital sepsis care.
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http://dx.doi.org/10.1097/CCM.0000000000003613 | DOI Listing |
NEJM AI
October 2024
Division of Biomedical Informatics, University of California, San Diego, San Diego.
Hospital quality measures are a vital component of a learning health system, yet they can be costly to report, statistically underpowered, and inconsistent due to poor interrater reliability. Large language models (LLMs) have recently demonstrated impressive performance on health care-related tasks and offer a promising way to provide accurate abstraction of complete charts at scale. To evaluate this approach, we deployed an LLM-based system that ingests Fast Healthcare Interoperability Resources data and outputs a completed Severe Sepsis and Septic Shock Management Bundle (SEP-1) abstraction.
View Article and Find Full Text PDFHealth Psychol Rev
December 2024
Department of Behavioural Science and Health, University College London, London, UK.
Prior research indicates that digital smoking cessation interventions can be effective, but little is known about their active ingredients. Therefore, this review aimed to examine the associations of content (behaviour change techniques [BCTs]), delivery features (delivery mode, readability, ease-of-use), and socioeconomic position with effectiveness. Systematic searches and hand searches were conducted from February to June 2023 to identify experimental evaluations of digital smoking cessation interventions published since 2004.
View Article and Find Full Text PDFJ Orthop
April 2025
Department of Physical Education, Banaras Hindu University, Varanasi, India.
Background: Running is practiced worldwide, but more than 50 % of runners suffer some form of musculoskeletal injury each year. Biomechanics of running is an important aspect of sports medicine and gait analysis is central in the study of running mechanics for prevention of injuries and enhancing performance.
Objectives: The purpose of this systematic literature review is to Saragiotto et al.
Front Nutr
January 2024
Department of Geriatrics, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, China.
The EAT-Lancet diet is a groundbreaking and comprehensive dietary framework that has garnered significant attention in the fields of nutrition, sustainability, and public health. We aimed to conduct a bibliometric study to investigate current status and hotspots in the field of EAT-Lancet diet based on the Web of Science Core Collection (WOSCC) database, and the documents of EAT-Lancet diet published from Jan 1, 2019 to Sep 1.2023 were extracted.
View Article and Find Full Text PDFJ Emerg Med
February 2024
Department of Emergency, Summa Health System, Akron, Ohio; Northeast Ohio Medical University, Rootstown, Ohio; U.S. Acute Care Solutions, Canton, Ohio.
Background: The Centers for Medicare and Medicaid Services (CMS) developed the Severe Sepsis and Septic Shock Performance Measure bundle (SEP-1) metric to improve sepsis care, but evidence supporting this bundle is limited and harms secondary to compliance have not been investigated.
Objective: This study investigates the effect of an emergency department (ED) sepsis quality-improvement (QI) effort to improve CMS SEP-1 compliance, looking specifically at antibiotic overtreatment and harm from fluid resuscitation.
Methods: This was a retrospective observational study conducted between March and July 2021 with patients for whom a sepsis order set was initiated.
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