Our study presented the long-term outcomes of coronary stenting and predictors of two-year outcomes in octogenarian patients with acute coronary syndrome. A total of 366 patients with STEMI, NSTEMI and unstable angina undergoing percutaneous coronary intervention (PCI). Results were assessed at a median follow up of 20 months. Hospital mortality in the group of patients older than 80 years was 8% and long-term mortality 21%. Chronic renal failure, cardiogenic shock, multi-vessel coronary disease, ejection fraction less than 35, left main coronary artery lesion were independent predictors of mortality. The best prognosis corresponded to those drug-eluting stents use, radial access and GP IIb/IIIa use in patients with ST-segment elevation myocardial infarction. Progression of cardiac and renal failure were the main causes of death during this period. Our results suggested that percutaneous coronary interventions in octogenarian patients with acute coronary syndrome was associated with good clinical and long-term outcomes. DES use, radial access and GP IIb/IIIa use in patients with ST-segment elevation myocardial infarction were associated with improved all-cause mortality in our population.

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