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Intestinal metastasis from breast invasive ductal carcinoma after a long latency: case report and literature review. | LitMetric

Intestinal metastasis from breast invasive ductal carcinoma after a long latency: case report and literature review.

Onco Targets Ther

Department of Radiation Oncology, The First Hospital, Jilin University, Changchun 130021, China,

Published: December 2018

AI Article Synopsis

  • Intestinal metastasis from breast cancer is rare and often misdiagnosed as a primary intestinal tumor due to nonspecific symptoms and a long time gap since the initial diagnosis.
  • A documented case highlights a patient who developed progressive abdominal issues 16 years post-mastectomy, eventually revealing that her symptoms were caused by metastatic breast cancer in the intestines, not a new primary tumor.
  • The case underscores the importance of considering intestinal metastasis in breast cancer patients presenting with gastrointestinal symptoms, as timely diagnosis and management can significantly improve outcomes.

Article Abstract

Intestinal metastasis from breast cancer (BC) is rarely encountered in clinical practice. Nonspecific symptoms and long latency result in misdiagnosis as a primary intestinal tumor. Therefore, increased awareness of bowel metastasis secondary to BC and a thorough understanding of the clinical and molecular features, and intervention of bowel metastasis are fundamental to avoid the delay of correct diagnosis and management. Herein, we documented a BC patient who experienced progressive bellyache and vomiting 16 years after simplified radical mastectomy. Abdominal CT scan revealed localized thickening of the small intestine wall and lumen narrowing, initially diagnosed as a primary intestinal tumor. The subsequent operation resolved the intestinal obstruction and confirmed the diagnosis of intestinal involvement of BC. Radical local treatment followed by systemic intervention contributed to a better outcome. Our case indicates that intestinal metastasis should be included in the diagnostic checklist in patients presented with any intestinal symptom even with a remote history of BC. Our case is of great value in its rarity and calls for the awareness of clinicians for this special entity to guarantee the accurate and prompt diagnosis and treatment, and optimize the patient's prognosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284526PMC
http://dx.doi.org/10.2147/OTT.S180949DOI Listing

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