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| http://dx.doi.org/10.1161/STROKEAHA.118.023955 | DOI Listing |
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Global Challenges in the Access of Endovascular Treatment for Acute Ischemic Stroke (Global MT Access).
Int J Stroke
January 2025
Department of Neurology, Grady memorial Hospital, Emory University, Atlanta, USA.
Background: Mechanical thrombectomy (MT) is the standard of care for eligible acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) since 2015.
Aim: Our aim was to determine the key challenges for MT implementation and access worldwide.
Methods: We conducted an international online survey consisting of 37 questions, distributed through the World Stroke Organization network, and as invited by co-authors between December 2022 and March 2023.
International practice patterns and perspectives on endovascular therapy for the treatment of cerebral venous thrombosis.
Int J Stroke
December 2024
Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Background: Cerebral venous thrombosis (CVT) accounts for 0.5-1% of all strokes. The role of endovascular therapy (EVT) in the management of CVT remains controversial and variations in practice patterns are not well known.
View Article and Find Full Text PDFARGONAUTE4 and the DNA demethylase REPRESSOR OF SILENCING 1C mediate dehydroascorbate-induced intergenerational nematode resistance in rice.
Plant Physiol
December 2024
Faculty of Bioscience Engineering, Department of Biotechnology, Ghent University, Proeftuinstraat 86 N1, Ghent 9000, Belgium.
Plants can transmit information to the next generation and modulate the phenotype of their offspring through epigenetic mechanisms. In this study, we demonstrate the activation of "intergenerational acquired resistance" (IAR) in the progeny of rice (Oryza sativa) plants exogenously treated with dehydroascorbate (DHA). The offspring of lifelong DHA-treated plants (DHA-IAR) were significantly less susceptible to the root-knot nematode Meloidogyne graminicola and partially inherited the DHA-induced transcriptional response found in the parental plants.
View Article and Find Full Text PDFClinical and Imaging Features Associated With Fast Infarct Growth During Interhospital Transfers of Patients With Large Vessel Occlusions.
Neurology
September 2024
From the Division of Experimental Neurology, Department of Neurosciences (A.W., J.D., R.L.), KU Leuven; Stanford Stroke Center (A.W., P.S., N.Y., M.M., S.K., S.C., G.W.A., M.G.L.), Palo Alto, CA; Institut de Psychiatrie et Neurosciences de Paris (IPNP) (P.S.), U1266, INSERM; Neurology Department (P.S.), Hôpital Fondation A. de Rothschild, Paris, France; Radiology Department (J.J.H.), Stanford University, Palo Alto, CA; and Department of Neurology (J.D., R.L.), University Hospitals Leuven, Belgium.
Background And Objectives: Acute ischemic stroke patients with a large vessel occlusion (LVO) who present to a primary stroke center (PSC) often require transfer to a comprehensive stroke center (CSC) for thrombectomy. Not much is known about specific characteristics at the PSC that are associated with infarct growth during transfer. Gaining more insight into these features could aid future trials with cytoprotective agents targeted at slowing infarct growth.
View Article and Find Full Text PDFBasilar artery occlusion management: An international survey of gender influence on management.
Interv Neuroradiol
August 2024
Department of Stroke Medicine, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, UK.
Background: The superiority of endovascular thrombectomy (EVT) over medical management was not established in two early basilar artery occlusion (BAO) randomized controlled trials. Despite this, many clinicians recommended EVT for acute BAO under certain circumstances. This paper aims to compare physicians' diagnostic and management strategies of BAO according to gender.
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