A new polyhydroxylated oleanane triterpenoid from the roots of .

Nat Prod Res

Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, People's Republic of China.

Published: January 2020

A new oleanane triterpenoid, 2,3,6,23,29-pentahydroxyolean-12-en-28- oic acid (), was isolated from the roots of , together with four known oleanane triterpenoids () and two known ursane triterpenoids (). The structure of compound was determined by extensive NMR and HR-ESI-MS data analysis. Compounds showed cytotoxicity against PC12 cell lines at a concentration of 50 M, and compound exhibited moderate neuroprotective activity against corticosterone induced PC12 cell death at the same concentration.

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Source
http://dx.doi.org/10.1080/14786419.2018.1525376DOI Listing

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