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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779036 | PMC |
| http://dx.doi.org/10.1136/adc.63.10.1272 | DOI Listing |
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Relationship between insulin-like growth factor I levels, early insulin treatment, and clinical outcomes of very low birth weight infants.
J Pediatr
May 2014
Department of Pediatrics, University of Cambridge, Addenbrooke's Hospital NHS Trust, Hills Road, Cambridge, United Kingdom.
Objectives: Insulin regulates the secretion of insulin-like growth factor I (IGF-I) in the newborn, and low levels of IGF-I have been linked to neonatal morbidity. As part of the Neonatal Insulin Replacement Therapy in Europe Trial, we investigated the impact of early insulin treatment on IGF-I levels and their relationship with morbidity and growth.
Study Design: Prospective cohort analyses of data collected as part of an international randomized controlled trial.
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