It is well known that up to 2% of chronic burn scar lesions can transform into malignant tumours, however, melanoma formation at these sites is extremely rare. This case report describes a burns case, which progressed to four melanomas in a 78-year-old male patient's little finger, 40 years after the initial incident. The patient underwent 3 mm punch biopsies, then digital amputation of the finger with pathology-proven melanoma. Histopathology investigation demonstrated three melanoma in situ and one invasive melanoma with a Breslow thickness of 1 mm. These findings are rare with few reports of melanoma in burn scars in the literature. This case report highlights the vigilance required from clinicians when performing skin examinations, and the importance of biopsies to newly pigmented lesions.
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http://dx.doi.org/10.1136/bcr-2018-227295 | DOI Listing |
N Engl J Med
January 2025
From the Departments of Medicine (D.R.) and Radiology (S.S.), Massachusetts General Hospital, the Departments of Medicine (D.R., S.D., J.A.S.) and Radiology (S.S.), Harvard Medical School, and the Department of Medicine, Brigham and Women's Hospital (S.D., J.A.S.) - all in Boston.
N Engl J Med
January 2025
Baylor College of Medicine, Houston, TX
Rev Soc Bras Med Trop
January 2025
Van Yuzuncu Yıl University School of Medicine, Department of Radiology, Van, Turkey.
Rev Soc Bras Med Trop
January 2025
Universidade Federal do Paraná, Departamento de Clínica Médica, Programa de pós-graduação em Medicina Interna e Ciências da Saúde, Curitiba, PR, Brasil.
Cryptococcal disease is the third most common invasive fungal infection in solid organ transplant recipients and is associated with high-morbidity and -mortality rates. Donor-derived Cryptococcus spp. infection typically manifests within the first month post-procedure and has historically been caused by C.
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