Fatigue continues to be a leading cause of military aviation mishaps. Several factors, including reversed shift missions, can negatively affect sleep patterns and increase the risk of fatigue due to sleep restriction. Currently, there is a lack of objective data regarding the current rest and activity patterns of military aviators across multiple operational conditions. The purpose of this descriptive study was to document the rest and activity patterns of U.S. Army aviators in operational training and garrison (routine) environments using wrist-worn actigraphy devices. Actigraphy data were collected from U.S. Army aviators in training ( = 20) and garrison ( = 77) environments for a period of 1 wk. Results from this study indicate that 90% of subjects in the training environment, even after accounting for small sleep bouts during the day, averaged less than the recommended 8 h of sleep daily across the recording week. Approximately half of subjects in garrison averaged less than 8 h of sleep daily after accounting for smaller sleep bouts. Sleep efficiency was relatively high and similar in both groups (∼84%). Subjects in the training group averaged significantly more time awake and less time sleeping than those in the routine garrison group. Moreover, subjects in training were exposed to more light during sleep than those in garrison. Training environments that are representative of deployed conditions restrict aviator restorative sleep. These results highlight the importance of continued research on aviator sleep and fatigue mitigation in operational environments.
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http://dx.doi.org/10.3357/AMHP.5193.2019 | DOI Listing |
Chem Biodivers
January 2025
Yangzhou University, College of Food Science and Engineering, Huayang west road, 225127, Yangzhou, CHINA.
The Lentinus edodes polysaccharide (LEP) was extracted with a new subcritical water extraction (SWE) enhanced with deep eutectic solvent (DES) method and then purified with a DEAE-52 cellulose column and a Sephadex G-100 column. Two purified polysaccharides (LEP1 and LEP2) were obtained and their structure, antioxidant activity, and immunomodulatory activity were analyzed. LEP1 and LEP2 were composed of mannose, glucose, and galactose with a molar ratio of 1:12.
View Article and Find Full Text PDFJ Hypertens
November 2024
Faculty of Sport Sciences, Universidad Europea de Madrid.
Objectives: The effects of acute physical exercise in patients with resistant hypertension remain largely unexplored compared with hypertensive patients in general. We assessed the short-term effects of acute moderate-intensity (MICE) and high-intensity interval exercise (HIIE) on the clinic (BP) and 24-h ambulatory blood pressure (ABP) of patients with resistant hypertension.
Methods: Using a crossover randomized controlled design, 10 participants (56 ± 7 years) with resistant hypertension performed three experimental sessions: MICE, HIIE, and control.
Proc Natl Acad Sci U S A
January 2025
Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-Universitat Politècnica de València, Valencia 46022, Spain.
The SWItch/Sucrose Non-Fermenting (SWI/SNF) complexes are evolutionarily conserved, ATP-dependent chromatin remodelers crucial for multiple nuclear functions in eukaryotes. Recently, plant BCL-DOMAIN HOMOLOG (BDH) proteins were identified as shared subunits of all plant SWI/SNF complexes, significantly impacting chromatin accessibility and various developmental processes in Arabidopsis. In this study, we performed a comprehensive characterization of mutants, revealing the role of BDH in hypocotyl cell elongation.
View Article and Find Full Text PDFJ Biomed Opt
January 2025
TU Dresden, Carl Gustav Carus Faculty of Medicine, Anesthesiology and Intensive Care Medicine, Clinical Sensing and Monitoring, Dresden, Germany.
Significance: The precise identification and preservation of functional brain areas during neurosurgery are crucial for optimizing surgical outcomes and minimizing postoperative deficits. Intraoperative imaging plays a vital role in this context, offering insights that guide surgeons in protecting critical cortical regions.
Aim: We aim to evaluate and compare the efficacy of intraoperative thermal imaging (ITI) and intraoperative optical imaging (IOI) in detecting the primary somatosensory cortex, providing a detailed assessment of their potential integration into surgical practice.
J Exp Orthop
January 2025
Centro Médico Profesional Las Mercedes, Av. Principal de Las Mercedes Caracas Venezuela.
Purpose: To assess platelet-rich plasma (PRP) changes in platelet and leucocyte count, insulin-like growth factor 1 (IGF-1), and interleukin 6 (IL-6) concentration after bilateral low-load knee extensions under blood flow restriction (BFR).
Methods: The present randomised controlled trial protocol will include two groups: the intervention group, which will undergo bilateral knee extensions under BFR, and the control group, which will perform bilateral knee extensions without BFR. Participants will be randomly allocated in a 1:1 ratio.
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