Background: The levels of corneal donation are insufficient to meet the demand for corneal transplantation in Japan. To overcome this problem, we started to routinely mention the possibility of corneal donation to the families of patients who died in our hospital's Urology Department in February 2008. In this study, we evaluated the effectiveness of this approach.
Methods: We retrospectively reviewed the medical records of the patients who died in the Department of Urology, St. Marianna University School of Medicine Hospital, and analyzed the patients' characteristics and information about corneal donation.
Results: In total, 211 patients died in our department between February 2008 and March 2017, and 155 patients were medically suitable corneal donors. We mentioned the possibility of corneal donation to 129 (83.2%) families, and 29 (18.7%) families agreed. Three families subsequently withdrew their consent. Finally, 26 (16.8%) of the families that were approached about corneal donation by urologists agreed to donate their relatives' corneas. Another 2 families voluntarily offered to donate their relatives' corneas. Thus, 28 (18.1%) of 155 medically suitable donors donated their corneas for transplantation. Twenty-six (92.8%) donors were 60 years or older and all donors were affected with malignant genitourinary tumors. Fifty-four (96.4%) corneas were successfully transplanted into recipients.
Conclusions: Even elderly patients who die of solid carcinoma can be an important source of corneal donors. In this study, we showed that routine referral by urologists increased corneal donation. If this approach were adopted by other departments, it might further increase the number of corneal donations.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.transproceed.2018.09.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identifying the greatest surgeon-perceived barriers and challenges in performing corneal transplantation in India.
Int Ophthalmol
January 2025
Keratoplasty Alliance International, Baltimore, Maryland, USA.
Objective: There is currently no systematic method of assessing limitations in performing corneal transplantation. The purpose of the study was to identify the limitations of performing corneal transplantation in India.
Design: Cross-sectional survey study.
Low-temperature vacuum evaporation as a novel dehydration process for the long-term preservation of transplantable human corneal tissue.
Cell Tissue Bank
January 2025
Academic Ophthalmology, Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.
Globally there is a shortage of available donor corneas with only 1 cornea available for every 70 needed. A large limitation to corneal transplant surgery is access to quality donor tissue due to inadequate eye donation services and infrastructure in many countries, compounded by the fact that there are few available long-term storage solutions for effectively preserving spare donor corneas collected in countries with a surplus. In this study, we describe a novel technology termed low-temperature vacuum evaporation (LTVE) that can effectively dry-preserve surplus donor corneal tissue, allowing it to be stored for approximately 5 years, shipped at room temperature, and stored on hospital shelves before rehydration prior to ophthalmic surgery.
View Article and Find Full Text PDFThe burden of medical contraindications to corneal donation: Time for review.
PLOS Glob Public Health
December 2024
Laboratory Biology, Engineering and Imaging for Ophthalmology, Health Innovation Campus, Faculty of Medicine, University Jean Monnet, Saint-Etienne, France.
Corneal graft (keratoplasty) is the most common allograft in the world, but the imbalance between the number of donors and the number of patients waiting for transplants is abysmal on a global scale and varies enormously from one country to another. The risk of transmission of systemic diseases from donor to recipient is demonstrably low. In over 50 years and an estimated 2.
View Article and Find Full Text PDFCorneal Transplantation in Australia Over 29 Years: A Retrospective Analysis of Medicare Data from 1994 to 2022.
Ophthalmic Epidemiol
December 2024
Department of Ophthalmology, The Royal Melbourne Hospital, Parkville, Australia.
Purpose: We aim to report the frequency and distribution of corneal transplantation, by age, sex, and state/territory, in Australia over a > 25-year period from 1994 to 2022, including during COVID-19 lockdowns.
Methods: Using data from Medicare, Australia's Government-funded health insurance scheme, we retrospectively analysed corneal transplants performed from January 1994 to December 2022.
Results: From 1994 to 2022, there were 27,536 corneal transplantation services processed by Medicare.
The impact of family history on corneal donation and transplantation attitudes: a survey-based study.
J Pak Med Assoc
December 2024
Department of Public Health, Necmettin Erbakan University, Konya, Turkey.
Objective: To assess how having a first-degree relative who underwent corneal transplantation influenced people's attitudes regarding corneal donation and transplantation.
Methods: The cross-sectional study was conducted between March 15 and April 15, 2023, in the Ophthalmology outpatient department and cornea division of Necmettin Erbakan University Faculty of Medicine Hospital, Konya, Turkiye, and comprised first-degree relatives of patients who had undergone corneal transplantation in group A and controls matched age and gender without family history of transplantation in group B. All the participants filled out a 13-item survey form regarding socio-demographic characteristics and their perspectives on corneal transplantation and donation.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!