The objective of this study was to determine the effect of the porcine circovirus type 2 (PCV2) vaccination on the levels of viremia, the number of viremic-positive pigs, and production performance [i.e. nursery mortality, post-weaning mortality, and average daily weight gain (ADWG)] under field conditions. There were 140 farrow-to-finish pig herds involved in this study. The vaccination of piglets was implemented in 82 of the 140 herds. In each herd blood samples were collected from sows and pigs in different age category. In addition, a questionnaire regarding the production performance was provided for each herd. Results demonstrate that the vaccination of piglets prevented the development of viremia in 23.2% of herds. Significant decreases in the levels of PCV2 DNA in serum and in the number of viremic pigs were also noted. These results indicate that the vaccination of piglets against PCV2 is a useful tool in controlling the PCV2 infection in herds with a high risk of a wide range of viral and bacterial agents, poor management strategies, and a low level of biosecurity practices.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.12834/VetIt.1009.5377.3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pig nasal and rectal microbiotas are involved in the antibody response to Glaesserella parasuis.
Sci Rep
January 2025
Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain.
Vaccination stands as one of the most sustainable and promising strategies to control infectious diseases in animal production. Nevertheless, the causes for antibody response variation among individuals are poorly understood. The animal microbiota has been shown to be involved in the correct development and function of the host immunity, including the antibody response.
View Article and Find Full Text PDFA lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets.
Virulence
December 2025
State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China.
Multiple porcine reproductive and respiratory syndrome virus (PRRSV) subtypes coinfect numerous pig farms in China, and commercial PRRSV vaccines offer limited cross-protection against heterologous strains. Our previous research confirmed that a PRRSV lineage 1 branch attenuated live vaccine (SD-R) provides cross-protection against HP-PRRSV, NADC30-like PRRSV and NADC34-like PRRSV. HP-PRRSV has undergone significant genetic variation following nearly two decades of evolution and has transformed into a subtype referred to as HP-like PRRSV, which also exhibits high pathogenicity.
View Article and Find Full Text PDFInterplay of swine acute diarrhoea syndrome coronavirus and the host intrinsic and innate immunity.
Vet Res
January 2025
Department of Preventive Veterinary Medicine, Research Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Swine acute diarrhoea syndrome coronavirus (SADS-CoV), a novel HKU2-related coronavirus of bat origin, is a newly emerged swine enteropathogenic coronavirus that causes severe diarrhoea in piglets. SADS-CoV has a broad cell tropism with the capability to infect a wide variety of cells from human and diverse animals, which implicates its ability to hold high risks of cross-species transmission. The intracellular antiviral immunity, comprised of the intrinsic and innate immunity, represents the first line of host defence against viral infection prior to the onset of adaptive immunity.
View Article and Find Full Text PDFInfluenza a Virus Detection at the Human-Swine Interface in US Midwest Swine Farms.
Viruses
December 2024
Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011, USA.
This study evaluated influenza A virus (IAV) detection and genetic diversity over time, specifically at the human-swine interface in breeding and nursery farms. Active surveillance was performed monthly in five swine farms in the Midwest United States targeting the employees, the prewean piglets at sow farms, and the same cohort of piglets in downstream nurseries. In addition, information was collected at enrollment for each employee and farm to assess production management practices, IAV vaccination status, diagnostic procedures, and biosecurity.
View Article and Find Full Text PDFEvaluation of the Effect of the Live Vaccine (Strain 168) in Ningxiang Pigs.
Vaccines (Basel)
November 2024
National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
[Background/Objectives] () is widespread in the global swine industry, leading to significant economic losses, and is particularly severe in native Chinese pig breeds. The Ningxiang pig, a well-known native breed in China, is susceptible to , exhibiting high morbidity and mortality rates. This study was designed to evaluate the clinical effectiveness of the live vaccine (strain 168).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!