Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3290/j.ohpd.a41679 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spatiotemporal control of translation in live zebrafish embryos via photoprotected mRNAs.
Commun Chem
January 2025
Institute of Biochemistry, University of Münster, Münster, Germany.
Translation of mRNA into protein is a fundamental process and tightly controlled during development. Several mechanisms acting on the mRNA level regulate when and where an mRNA is expressed. To explore the effects of conditional and transient gene expression in a developing organism, it is vital to experimentally enable abrogation and restoration of translation.
View Article and Find Full Text PDFReconstructing the first COVID-19 pandemic wave with minimal data in England.
Epidemics
January 2025
Department of Biology, University of Oxford, United Kingdom. Electronic address:
Accurate measurement of exposure to SARS-CoV-2 in the population is crucial for understanding the dynamics of disease transmission and evaluating the impacts of interventions. However, it was particularly challenging to achieve this in the early phase of a pandemic because of the sparsity of epidemiological data. We previously developed an early pandemic diagnostic tool that linked minimum datasets: seroprevalence, mortality and infection testing data to estimate the true exposure in different regions of England and found levels of SARS-CoV-2 population exposure to be considerably higher than suggested by seroprevalence surveys.
View Article and Find Full Text PDFMicrobial molecules, metabolites, and malignancy.
Neoplasia
January 2025
Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA; Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address:
Research elucidating the role of the microbiome in carcinogenesis has grown exponentially over the past decade. Initially isolated to associative studies on colon cancer development, the field has expanded to encompass nearly every solid and liquid malignancy that may afflict the human body. Investigations are rapidly progressing from association to causation and one particular area of causal effect relates to microbial metabolites and how they influence cancer development, progression, and treatment response.
View Article and Find Full Text PDFHealthcare provider perspectives on integrating HIV care into cancer centers in Malawi, South Africa, Uganda, and Zimbabwe.
Transl Oncol
January 2025
Faculty of Medicine and Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
Background: In East and Southern Africa, treatment of people with concomitant cancer and HIV is complicated by siloed service delivery pathways, which exacerbate barriers to care and impact clinical decision-making. Integrating HIV care into cancer treatment centers may improve service delivery and overall patient outcomes.
Methods: We administered a questionnaire to clinicians and support staff at tertiary cancer referral centers in Malawi, Zimbabwe, Uganda, and South Africa to assess level of concern about clinical management of people with HIV (PWH) and cancer, barriers to integrating HIV service delivery into cancer treatment delivery, and beliefs related to HIV, antiretroviral therapy (ART), and integrated care.
IFN-mediated lncRNA-ISL promotes SVV infection through G1P3.
Vet Microbiol
December 2024
Chongqing Academy of Animal Sciences, Chongqing 402460, China; Southwest University, College of Veterinary Medicine, Chongqing 400715, China; Department of Infectious Diseases, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; State Key Laboratory of Silkworm Genome Biology, Chongqing 400715, China. Electronic address:
lncRNAs play important regulatory roles in almost every aspect of physiological processes. However, the mechanisms by which animal-encoded lncRNAs regulate the interaction of viral infection with host antiviral immunity are unknown. To explore the mechanisms of lncRNA regulation of SVV infection and interferon responses.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!