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Article Synopsis
  • Emphysematous pyelonephritis (EPN) is a severe urinary tract infection that can lead to high mortality rates, particularly in cases with underlying conditions, but it's rarely reported.
  • A 32-year-old pregnant woman with type 2 diabetes experienced worsening symptoms of pyelonephritis, leading to a diagnosis of EPN through imaging techniques.
  • Successful treatment involved antibiotic therapy, emphasizing the importance of early diagnosis and customized treatment approaches to safeguard both maternal and fetal health during pregnancy.
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Background Diabetes mellitus (DM) is a prevalent predisposing factor for urinary tract infections (UTIs). Among hospitalized patients with acute pyelonephritis, UTIs are more common, severe, and associated with worse outcomes, particularly in those with type 2 DM. Pyelonephritis in DM patients is more frequently bilateral and linked to greater complications, with 90% of emphysematous pyelonephritis (EMPN) and cystitis cases occurring in diabetic individuals.

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Clinical image: emphysematous pyelonephritis.

Oxf Med Case Reports

December 2024

Section of Infectious Disease, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.

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