Limited studies have explored the association between ambient temperature and the disease burden of pesticide poisoning. Our study aims to estimate associations between daily mean temperature and pesticide poisoning incidence with lag effect. A distributed lag nonlinear model with Poisson distribution was used to examine the nonlinear lagged effects of ambient temperature on pesticide poisoning incidence. Overall, the estimated effects of temperature on pesticide poisoning incidence were non-linear, with higher relative risks (RRs) at hotter temperatures. It was found that the high temperature had acute and short-term effects and then declined rapidly along the lag days with the maximum risk occurring 0 day of exposure. Considering the 5-day cumulative RR for daily mean temperature, the temperature generally showed a positive association with the pesticide poisoning incidence, achieving the maximum risk at 31°C. In general, pesticide poisoning incidence increased with higher temperatures, with the strongest effects occurring shortly.
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http://dx.doi.org/10.1080/09603123.2018.1558185 | DOI Listing |
BMJ Open
January 2025
National Poison Centre, Universiti Sains Malaysia, Georgetown, Penang, Malaysia
Objective: Glyphosate is widely used in Malaysian agriculture but poses a significant under-reported public health concern due to poisoning. This paper aims to study the epidemiology of glyphosate poisoning in Malaysia, assessing severity, identifying risk factors, and high-risk groups.
Setting: All glyphosate-related data of the Malaysia National Poison Centre from 2006 to 2023.
Indian J Occup Environ Med
December 2024
Viral Research and Diagnostic Laboratory (VRDL), Government Medical College, Patiala, Punjab, India.
Pesticides induce oxidative DNA damage and genotoxic effects such as DNA single-strand breaks (SSBs), double-strand breaks (DSBs), DNA adducts, chromosomal aberrations, and enhanced sister chromatid exchanges. Such DNA damage can be repaired by DNA repair mechanisms. In humans, single nucleotide polymorphisms (SNPs) are present in DNA repair genes involved in base excision repair (BER) (, and nucleotide excision repair (NER) (, , , and ), and double-strand break repair (DSBR) ( and ).
View Article and Find Full Text PDFJ Food Sci Technol
February 2025
Department of Chemical Engineering, Indian Institute of Technology, New Delhi, 110062 India.
Unlabelled: The use of pesticides in agricultural produce is continuously increasing and it raises the question of whether the food is safe or not. Only 0.1% of the sprayed pesticide reaches its target and the rest acts as a contaminant in soil and the environment, thus contaminating the future foods as well.
View Article and Find Full Text PDFTalanta
January 2025
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, PR China. Electronic address:
Monitoring of p-nitrophenol (PNP) and 3-methyl-4-nitrophenol (PNMC) in human urine and environmental water is of great importance for human health assessment and environmental protection, as they are both urinary metabolites of some poisonous pesticides and priority environmental pollutants. However, efficient extraction of trace levels of PNP and PNMC from complex matrices remains challenging. This study presented the synthesis of histidine-modified ZIF-90 on natural eggshell membrane (ESM@His-ZIF-90) via a facile one-step in-situ growth strategy, and its application as an adsorbent for dispersive membrane extraction (DME) of PNP and PNMC in human urine and environmental water.
View Article and Find Full Text PDFLangmuir
January 2025
Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, Shu and K. C. Chien and Peter Farrell Collaboratory, University of California San Diego, La Jolla, California 92093, United States.
Poisoning by organophosphate (OP) nerve agents remains a pressing global threat due to their extensive use in chemical warfare agents and pesticides, potentially causing high morbidity and mortality worldwide. This urgent need for effective countermeasures has driven considerable interest in innovative detoxification approaches. Among these, nanoparticle technology stands out for its multifunctional potential and wide-ranging applications.
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