AI Article Synopsis
- A 24-year-old man with a history of bone marrow transplant for aplastic anemia and chronic graft versus host disease (GVHD) developed worsening swelling due to large pericardial effusion.
- A CT scan and echocardiogram indicated early signs of cardiac tamponade, leading to an emergency procedure to drain the fluid.
- The diagnosis of pericardial graft versus host disease emphasizes the importance of recognizing this serious complication, which can have life-threatening consequences and necessitates prompt medical attention.
Article Abstract
A 24-year-old man with previous matched unrelated donor allogenic bone marrow transplant for aplastic anaemia and chronic graft versus host disease on steroid taper presented with progressively worsening anasarca. CT revealed large pericardial effusion, while echocardiogram was concerning for early tamponade physiology. He underwent emergent pericardiocentesis with pericardial drain placement. Extensive rheumatological and infectious work-up was unrevealing with patient's presentation attributed to pericardial graft versus host disease. This highlights the need of physicians to be aware of pericardial serositis as a complication of graft versus host disease due to its life-threatening complications, which require immediate intervention.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301513 | PMC |
| http://dx.doi.org/10.1136/bcr-2018-227507 | DOI Listing |
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