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Complete metabolic response of metastatic castration-resistant neuroendocrine carcinoma of the prostate after treatment with RRx-001 and reintroduced platinum doublets. | LitMetric

AI Article Synopsis

  • A patient with advanced neuroendocrine prostate cancer received multiple previous treatments before being part of a Phase II clinical trial.
  • The patient was treated with RRx-001, a dual inhibitor targeting CD-47 and SIRP-α.
  • After undergoing platinum-based chemotherapy, the patient achieved a complete metabolic response, indicating significant improvement in their condition.

Article Abstract

Presented herein is the case of a heavily pretreated patient with high-grade neuroendocrine prostate cancer that achieved a complete metabolic response on platinum-based chemotherapy after treatment with the dual CD-47 and SIRP-α inhibitor, RRx-001, in a Phase II clinical trial.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293266PMC
http://dx.doi.org/10.1002/ccr3.1880DOI Listing

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