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Glutathione peroxidase 4 overexpression induces anomalous subdiffusion and impairs glioblastoma cell growth.
J Biol Eng
December 2024
Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.
Glioblastoma tumors are the most common and aggressive adult central nervous system malignancy. Nearly all patients experience disease progression, which significantly contributes to disease mortality. Recently, it has been suggested that recurrent tumors may be characterized by a ferroptosis-prone phenotype with a significant decrease in glutathione peroxidase 4 (GPx4) expression.
View Article and Find Full Text PDFCase Report: Unveiling an anomalous diaphragmatic paraganglioma mimicking a hepatic tumor.
F1000Res
December 2024
Division of Radiology, Jackson Memorial Hospital, Miami, Florida, USA.
Paragangliomas are rare neuroendocrine tumors, often associated with catecholamine secretion. These tumors can arise in various locations, with the majority found in the abdomen and pelvis, while a smaller percentage occurs in the thorax and head and neck regions. Diaphragmatic paragangliomas are exceedingly rare, with only two documented cases in the literature.
View Article and Find Full Text PDFEndoscopic Ultrasound-Guided Diagnosis of Gallbladder Mixed Neuroendocrine Non-Neuroendocrine Tumor With an Anomalous Pancreaticobiliary Junction.
ACG Case Rep J
December 2024
Department of Gastroenterology, Tufts Medical Center, Boston, MA.
Mixed neuroendocrine non-neuroendocrine neoplasms are exceedingly rare tumors, especially those of gallbladder origin. Anomalous pancreaticobiliary junction is an uncommon congenital abnormality that can predispose various types of hepatobiliary malignancies. We present an unusual case of a 46-year-old woman with anomalous pancreaticobiliary junction who presented to the emergency department with nausea, vomiting, and right upper quadrant pain.
View Article and Find Full Text PDFVideothoracoscopic management of hemoptysis due to anomalous bronchial vessel treated with multiple bronchial artery embolizations: a case report.
Front Pediatr
November 2024
General and Thoracic Pediatric Surgery Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Article Synopsis
- Hemoptysis, the coughing up of blood, can stem from various serious underlying conditions, but often involves high-pressure bronchial arteries; Bronchial artery embolization (BAE) is typically the first-line treatment despite varying long-term success rates.
- A 12-year-old boy with a history of massive hemoptysis underwent multiple BAEs and recent imaging confirmed the location of previous coils; however, he experienced another episode where traditional intervention was complicated by prior treatments.
- The medical team opted for a thoracoscopic approach, successfully isolating and ligating the problematic vessel, leading to the patient's stabilization and discharge after four days.
Indocyanine Green-Guided Pulmonary Resection for Lung Cancer With Anomalous Systemic Arterial Supply to the Basal Segment.
J UOEH
December 2024
Department of Respiratory Medicine, Iizuka Hospital, Japan.
A 78-year-old male who was undergoing treatment for diabetes was referred to our department after a chest X-ray revealed an abnormal shadow in the left upper lung field. A chest contrast-enhanced CT showed a tumor in the left upper lobe and a cystic lesion in the left lower lobe. Two aberrant arteries branching from the aorta were identified near the cyst.
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