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| http://dx.doi.org/10.1016/j.jdcr.2018.10.010 | DOI Listing |
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Drug-Induced Alopecia Areata From Upadacitinib.
Cureus
August 2024
Dermatology, Temple University Hospital, Philadelphia, USA.
Article Synopsis
- - A 55-year-old woman developed alopecia areata (AA) after a year of treatment with upadacitinib for her atopic dermatitis.
- - This case is significant as it suggests a potential link between upadacitinib and the onset of AA, a connection not previously documented.
- - The report emphasizes the usual timeline for drug-induced hair loss and prompts further investigation into the possibility of upadacitinib causing such side effects.
Topical Minoxidil Overdose in a Young Man With Androgenetic Alopecia: A Case Report.
Cureus
June 2024
Human Anatomy and Histology, I.M. Sechenov First Moscow State Medical University, Moscow, RUS.
Minoxidil is an effective and relatively safe topical drug that is used to treat androgenetic alopecia and other types of alopecia. This active ingredient is used in dermatology as a hair growth stimulant; however, the use of solutions containing minoxidil can be accompanied by a variety of cardiovascular systemic side effects. In this case report, we describe the case of a 23-year-old man who presented with complaints of dizziness, blurred vision, general malaise, fatigue, and feeling pre-syncopal while standing after applying large amounts of topical minoxidil solution for three days in a row.
View Article and Find Full Text PDFDNA methylation of microRNA-365-1 induces apoptosis of hair follicle stem cells by targeting .
Noncoding RNA Res
September 2024
Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Article Synopsis
- The study investigates the role of DNA methylation in chemotherapy-induced hair loss (alopecia) using a mouse model to better understand the underlying biological processes involved.
- Researchers assessed hair follicle stem cell (HFSC) health through various staining techniques, molecular assays, and analysis of key HFSC markers and DNA methylation levels, comparing normal and drug-induced conditions.
- Results indicated a significant increase in cell apoptosis and a reduction in HFSC marker expression in CTX-treated mice, highlighting the complex relationship between DNA methylation and hair loss due to chemotherapeutic drugs.
Sebaceous gland atrophy due to seborrheic dermatitis in a patient with alopecia: A potential pitfall.
J Cutan Pathol
July 2024
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Seborrheic dermatitis is an inflammatory condition that usually presents with erythema, scaly greasy papules, and plaques affecting sebaceous gland-rich areas and predominantly involving the face and scalp. The diagnosis of seborrheic dermatitis can often be rendered based on the clinical presentation. However, in certain cases, a biopsy can be useful to distinguish it from clinical mimics such as psoriasis, discoid lupus, and rosacea.
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