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http://dx.doi.org/10.1038/s41422-018-0110-y | DOI Listing |
Int J Mol Sci
January 2025
A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
Apurinic/apyrimidinic (AP) sites are endogenous DNA lesions widespread in human cells. Having no nucleobases, they are noncoding and promutagenic. AP site repair is generally initiated through strand incision by AP endonuclease 1 (APE1).
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Center of Clinical and Preclinical Research MEDIPARK, Pavol Jozef Šafarik University, 04011 Košice, Slovakia.
Breast cancer (BC) is one of the most prevalent forms of cancer globally, and has recently become the leading cause of cancer-related mortality in women. BC is a heterogeneous disease comprising various histopathological and molecular subtypes with differing levels of malignancy, and each patient has an individual prognosis. Etiology and pathogenesis are complex and involve a considerable number of genetic alterations and dozens of alterations in non-coding RNA expression.
View Article and Find Full Text PDFJ Biomech
January 2025
Clinic for Orthopedics, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:
In order to improve the understanding foot function in the presence of planovalgus foot deformity, functional joint center determination is applied to the ankle and midfoot for application in 3D-gait analysis. Gait data of 36 patients with planovalgus (PV) foot deformity as well as of 33 typically developing (TD) subjects were collected using foot markers according to the Heidelberg Foot Measurement method. During single-limb stance subjects performed a circular movement of the foot and ankle (CIR) by drawing a circle with the hallux in the air.
View Article and Find Full Text PDFACS Nano
January 2025
Jiangsu Key Laboratory of Frontier Material Physics and Devices, School of Physical Science and Technology, Soochow University, Suzhou, Jiangsu 215006, China.
Circular differential scattering (CDS) spectroscopy has been developed as a powerful method for the characterization of the optical activity of individual plasmonic nanostructures and their complexes with chiral molecules. However, standard measurement setups often result in artifacts that have long raised concerns on the interpretation of spectral data. In fact, the detection limit of CDS setups is constrained by the high level of artifacts, to ±10%.
View Article and Find Full Text PDFACS Nano
January 2025
Department of Physics, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan.
We have found that surface superstructures made of "monolayer alloys" of Tl and Pb on Si(111), having giant Rashba effect, produce nonreciprocal spin-polarized photocurrent via circular photogalvanic effect (CPGE) by obliquely shining circularly polarized near-infrared (IR) light. CPGE is here caused by the injection of in-plane spin into spin-split surface-state bands, which is observed only on Tl-Pb alloy layers but not on single-element Tl nor Pb layers. In the Tl-Pb monolayer alloys, despite their monatomic thickness, the magnitude of CPGE is comparable to or even larger than the cases of many other spin-split thin-film materials.
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