Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of antifungal efficacy require salvage therapy in the treatment of some patients. In a retrospective review of nine patients with coccidioidal meningitis treated with isavuconazole, successful therapy was seen in three patients and stable disease was confirmed in six patients. Isavuconazole may be a useful addition to the therapeutic choices currently available for coccidioidal meningitis.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395935 | PMC |
| http://dx.doi.org/10.1128/AAC.02232-18 | DOI Listing |
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