1,1,1,3,3,3-Hexafluoropropan-2-ol (HFIP) was found to be effective for the Bischler indole synthesis under microwave irradiation in the absence of a metal catalyst. Under the catalysis of HFIP, a wide range of α-amino arylacetones were successfully transformed into indole derivatives with moderate to good yields.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321335 | PMC |
| http://dx.doi.org/10.3390/molecules23123317 | DOI Listing |
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