A 38-year-old woman presented with fever, right flank pain, and a clinical diagnosis of pyelonephritis. Work-up revealed the presence of a crossing arterial branch causing obstruction of the superior infundibulum of the right kidney, which is an uncommon cause of nephralgia and urinary infection initially described by Fraley in 1966. Intravenous urography, retrograde pyelography, and angiography remain the mainstay of diagnosis, much as in the initial descriptions of this entity. [131I]Hippuran imaging, with analysis of the upper and lower pole regions of interest, provides a simple yet powerful method of evaluating functional and excretory changes in the superior infundibulum, and has proved more efficacious than previously reported whole-kidney renograms. Renal scintigraphy represents a relatively noninvasive method of serial functional examination in this disorder. Ultrasound imaging, by monitoring upper-pole dilatation, may provide complementary morphologic information important for long-term follow-up.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF02926548 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A deep learning approach to predict differentiation outcomes in hypothalamic-pituitary organoids.
Commun Biol
December 2024
Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
We use three-dimensional culture systems of human pluripotent stem cells for differentiation into pituitary organoids. Three-dimensional culture is inherently characterized by its ability to induce heterogeneous cell populations, making it difficult to maintain constant differentiation efficiency. That is why the culture process involves empirical aspects.
View Article and Find Full Text PDFThyroid Hormones and Co-workers: An Overview.
Methods Mol Biol
November 2024
Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), Consejo Superior de Investigaciones Científicas (CSIC)-Universidad Autónoma de Madrid (UAM), Madrid, Spain.
The hypothalamus secretes the thyroid-releasing hormone (TRH) that induces the pituitary gland to release the thyroid-stimulating hormone (TSH) which stimulates thyroid follicular cells to release the thyroid hormones (THs), thyroxine (T4), and triiodothyronine (T3). The process of synthesizing T3 and T4 hormones involves various enzymatic steps, starting with the iodination of L-tyrosine residues present in the protein thyroglobulin. Thyroid hormones are released into the bloodstream, where they bind to thyroid hormone distributor proteins (THDPs) which transport them in the circulation.
View Article and Find Full Text PDFThe goat PRLR gene: mRNA expression, association analysis of InDel variants with body weight and growth traits.
Gene
January 2025
College of Veterinary Medicine/Shaanxi Centre of Stem Cells Engineering & Technology, Northwest Agriculture & Forestry University, Yangling, Shaanxi, China. Electronic address:
Prolactin is a single-chain peptide hormone produced by the anterior pituitary gland and plays an important role in the reproductive development of mammals. Therefore, we investigated the expression of the PRLR gene in various goat tissues during distinct developmental stages, as well as the correlation between the 16 bp InDel and growth traits in goats. The study findings demonstrated a consistent expression and distribution of PRLR in both yearling and adult goat tissues, with the highest levels observed in the testis.
View Article and Find Full Text PDFA pituitary gland squeezed upward by intrasellar kissing carotid arteries: Mimicking a pituitary microadenoma.
Surg Neurol Int
October 2024
Department of Neurosurgery, Kagoshima University, Kagoshima, Japan.
Background: Intrasellar kissing carotid arteries are a rare variant in which bilateral internal carotid arteries run very near each other at their cavernous sinus portion. We encountered a woman with the pituitary gland mimicking a pituitary microadenoma because the pituitary gland was compressed bilaterally by intrasellar kissing carotid arteries.
Case Description: A 61-year-old woman with a chronic headache underwent magnetic resonance imaging, which revealed a sellar mass measuring 10.
GHRH and the prostate.
Rev Endocr Metab Disord
November 2024
Departamento de Biología de Sistemas. Unidad de Bioquímica y Biología Molecular (Research group "Cánceres de origen epitelial"), Universidad de Alcalá, Campus Científico-Tecnológico, 28871, Alcalá de Henares, Madrid, Spain.
Article Synopsis
- In the late 1960s and early 1970s, researchers isolated and studied hypothalamic regulatory hormones, discovering both normal and tumor tissues can produce growth hormone-releasing hormone (GHRH).
- GHRH receptors, particularly the pituitary-type (pGHRH-R), are predominantly found in the anterior pituitary but also in other body cells and various cancers, including prostate cancer, with splice variants detected in these tissues.
- GHRH activates multiple signaling pathways that promote cell survival and proliferation, making GHRH receptors potential drug targets, especially in prostate conditions, with recent antagonists showing enhanced anticancer and anti-inflammatory effects.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!