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Approaches, Barriers, and Facilitators in Statewide Initiative to Combat Opioid Overdose: A Narrative Review of Ohio's Experiences During the HEALing Communities Study.
Prehosp Emerg Care
January 2025
Department of Emergency Medicine, MetroHealth Medical Center, Cleveland, Ohio.
Objectives: Opioid-associated fatal and non-fatal overdose rates continue to rise. Prehospital overdose education and naloxone distribution (OEND) programs are attractive harm-reduction strategies, as patients who are not transported by EMS after receiving naloxone have limited access to other interventions. This narrative summary describes our experiences with prehospital implementation of evidence-based OEND practices across Ohio as part of the HEALing Communities Study (HCS).
View Article and Find Full Text PDFWould Provision of Take Home Naloxone Kits by Emergency Medical Services be Perceived as Acceptable to People at Risk of Opioid Overdose? A Qualitative Study.
Prehosp Emerg Care
January 2025
Health Service Research, Swansea University Medical School, Swansea, Wales.
Objectives: Take home naloxone kits can reduce mortality, but we know little about how they are perceived by people with lived experience of opioid use. Provision of naloxone in the community has been shown to significantly reduce mortality from opioid overdose. Currently, this is predominantly through drug treatment support services but expanding provision through other services might be effective in increasing kit take-up and mortality reduction.
View Article and Find Full Text PDFTake-Home Naloxone, Release From Jail, and Opioid Overdose-A Piece of the Puzzle.
JAMA Netw Open
December 2024
SEICHE Center for Health and Justice, Yale School of Medicine, New Haven, Connecticut.
Agent-Based Model of Combined Community- and Jail-Based Take-Home Naloxone Distribution.
JAMA Netw Open
December 2024
Decision and Infrastructure Sciences Division, Argonne National Laboratory, Lemont, Illinois.
Importance: Opioid-related overdose accounts for almost 80 000 deaths annually across the US. People who use drugs leaving jails are at particularly high risk for opioid-related overdose and may benefit from take-home naloxone (THN) distribution.
Objective: To estimate the population impact of THN distribution at jail release to reverse opioid-related overdose among people with opioid use disorders.
Comparative Effectiveness of Buprenorphine/Naloxone and Methadone on Methamphetamine/Amphetamine Use Among People with Opioid Use Disorder in Canada.
Subst Use Addctn J
November 2024
British Columbia Centre on Substance Use, Vancouver, BC, Canada.
Article Synopsis
- The study investigates the impact of opioid agonist therapy (OAT) on methamphetamine and amphetamine use among individuals with opioid use disorder (OUD) in Canada, comparing buprenorphine/naloxone and methadone.
- Conducted over 24 weeks, data from a pan-Canadian trial highlighted that both treatments showed no significant effect on reducing methamphetamine/amphetamine use, as assessed through drug testing and self-reporting.
- Despite methamphetamine/amphetamine use being prevalent among participants, results indicated that neither treatment method led to notable changes in their usage patterns throughout the study period.
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