Background: The purpose of this study was to assess changes in vocal function over time following supracricoid partial laryngectomy with cricohyoidoepiglottopexy (SCL-CHEP).
Methods: A total of 17 patients who underwent SCL-CHEP for laryngeal squamous cell carcinoma between 2007 and 2015 were reviewed. We examined maximum phonation time (MPT), mean airflow rate (MFR), voice intensity, the grade, roughness, breathiness, asthenia, and strain (GRBAS) scale, Voice Handicap Index-10 (VHI-10), and voice-related quality of life (V-RQOL) scores. To assess changes over time in these parameters, we set 3 evaluation periods after surgery: within the first 12 months (term A), 13-36 months (term B), and after 37 months (term C).
Results: The mean MPT, MFR, G and B GRBAS subscale, VHI-10, and V-RQOL scores improved significantly over time postoperatively.
Conclusion: Multiple vocal function parameters improved significantly with time due to self-adaptation to a newly created glottis after surgery.
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http://dx.doi.org/10.1002/hed.25487 | DOI Listing |
Alzheimers Dement
December 2024
IPSIBAT (CONICET/National University of Mar del Plata), Mar del Plata, Buenos Aires, Argentina.
Background: Neuropsychological language assessment batteries usually include connected speech tasks (e.g. the description of a picture).
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
January 2025
Department of Otolaryngology and Phoniatrics-Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Introduction: There are inconsistencies in how different endoscopic procedures to manage Bilateral Vocal Fold Immobility (BVFI) have been described in the literature. This limits our ability to compare functional outcomes. There is no unifying international terminology available that precisely describes the anatomical boundaries and extent of the different types of treatment.
View Article and Find Full Text PDFFront Behav Neurosci
December 2024
Department of Biology, Miami University, Oxford, OH, United States.
There is a striking sex bias in the prevalence and severity of autism spectrum disorder (ASD) with 80% of diagnoses occurring in males. Because the molecular etiology of ASD is likely combinatorial, including interactions across multiple genetic and environmental factors, it is difficult to investigate the physiological mechanisms driving sex-specific differences. Loss of function mutations in result in dysregulated mTORC1 signaling and underlie a multi-system disorder known as tuberous sclerosis (TSC).
View Article and Find Full Text PDFPoult Sci
December 2024
Animal Sciences, Purdue University, West Lafayette, IN, USA. Electronic address:
We tested Pekin ducks with playbacks of 5 different vocalizations plus a no noise and white noise stimulus as our controls (N = 15 ducks/sex/treatment). The "AM long" call is a common vocalization made by both sexes. "Honk" is also produced by both sexes and is thought to be an alarm or distress call.
View Article and Find Full Text PDFJ Acoust Soc Am
December 2024
Department of Head and Neck Surgery, University of California Los Angeles, Los Angeles, California 90095-1794, USA.
Previous studies of laryngeal and respiratory control of the voice source often focus on main effects of individual control parameters but not their interactions. The goal of this study is to systematically identify important interaction effects in laryngeal and respiratory control of the voice source and vocal fold contact pressure in a three-dimensional voice production model. Computational simulations were performed with parametric variations in vocal fold geometry, stiffness, prephonatory glottal gap, and subglottal pressure.
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