Blood culture-negative endocarditis presents a clinical and diagnostic challenge. Here, we describe a patient with a delayed diagnosis of endocarditis. < The aim of this report is to highlight the importance of species as a cause of culture-negative endocarditis and to illustrate the challenges it poses in diagnosis and treatment.>.
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http://dx.doi.org/10.1016/j.jccase.2015.08.011 | DOI Listing |
Front Cell Infect Microbiol
January 2025
Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
[This corrects the article DOI: 10.3389/fcimb.2024.
View Article and Find Full Text PDFLancet Infect Dis
January 2025
Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada.
The incidence of syphilis has increased steadily over the past 25 years. Undiagnosed cases have presumably increased in the same proportions, and rare complications are at particularly high risk of being unrecognised. A previously healthy 60-year-old man presented with rapidly progressive heart failure and severe aortic and mitral valve insufficiency, with direct valvular destruction and preservation of the aortic valve annulus and aortic root.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department VI Cardiology-Cardiovascular Surgery, "Victor Babes" University of Medicine and Pharmacy of Timișoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
: Thoracic aortic aneurysms (TAAs) are potentially life-threatening medical conditions, and their etiology involves both genetic and multiple risk factors. endocarditis is one of the most frequent causes of blood culture-negative infective endocarditis (BCNIE) in patients with previous cardiac surgery. Our review aims to emphasize the importance of genetic testing in patients with thoracic aortic aneurysms but also the importance of additional testing in patients with suspected endocarditis whose blood cultures remain negative.
View Article and Find Full Text PDFEur J Cardiothorac Surg
December 2024
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany.
Objectives: The study aimed to analyse outcomes of surgery for blood culture-negative infective endocarditis (BCNIE) and to evaluate the role of molecular biological imaging.
Methods: Patients undergoing surgery for native or prosthetic valve endocarditis from 2013 to 2022 were analysed regarding blood culture-positive infective endocarditis (BCPIE) and BCNIE. For laboratory diagnostics in BCNIE, excised valves or prostheses underwent conventional microbiological culture and fluorescence in situ hybridization combined with 16S rRNA-gene polymerase chain reaction and sequencing (FISHseq).
Pediatr Infect Dis J
December 2024
From the Division of Infectious Diseases, Department of Paediatrics.
Bartonella quintana is a rare but important cause of culture-negative endocarditis, classically associated with body lice infestation. We report the first known pediatric case of Bartonella quintana endocarditis associated with head lice. The importance of sending targeted testing for this organism in at-risk patients, ideally on tissue specimens, is emphasized.
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