AI Article Synopsis
- Two new anthraquinone dimers (1, 2) and several known compounds were isolated from the marine fungus Aspergillus versicolor as part of ongoing research.
- The structures of these compounds were analyzed using techniques like NMR and HRMS, confirming their configurations.
- Compounds 1 and 2 showed selective antibacterial effects against Staphylococcus aureus, while compound 6 demonstrated moderate cytotoxicity against human cancer cells.
Article Abstract
As a continue investigation of the bioactive secondary metabolites from marine derived fungi, two new anthraquinone dimers (1, 2), along with three known anthraquinones (3-5) and two known xanthones (6, 7) were isolated from the marine-derived fungus Aspergillus versicolor. Their structures, including the absolute configurations, were elucidated by NMR, HRMS, and comparison with reported ones. Among them, compounds 1 and 2 were identified as anthraquinone dimers which dimerized by a rare C-O-C ether linkage, and both of them showed selective antibacterial activity against Gram-positive Staphylococcus aureus; whilst compound 6 exhibited moderate cytotoxicity against human cancer cell lines.
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| http://dx.doi.org/10.1016/j.fitote.2018.11.015 | DOI Listing |
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