The Waldmann's disease is a primitive intestinal lymphangectasia. This exsudative enteropathy initiates a protein leakage by the digestive tract. Clinically, this syndrome is characterised by oedemas and biologically by hypoprotidemia and loss of lymphocytes T CD4+, which increases a risk for infections. Here, we describe a patient's case for whom the protein loss was aggravated by a nephrotic syndrome.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1684/abc.2018.1398 | DOI Listing |
Eur Heart J Case Rep
July 2024
Department of Cardiac, Thoracic and Vascular Surgery, National University Heart Center, Singapore City, Singapore.
Background: Mitral annular calcification (MAC) is common in the elderly. Extensive calcification has been historically challenging for the cardiac surgeons, with traditional surgical approaches carrying significant risks. Less invasive approaches have recently been explored in an attempt to reduce this risk.
View Article and Find Full Text PDFJ Inherit Metab Dis
November 2024
University Children's Hospital Zurich and Children's Research Center, University of Zurich, Zurich, Switzerland.
J Med Chem
July 2024
Department of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo 05508-000, Brazil.
This study presents a new approach for identifying myeloperoxidase (MPO) inhibitors with strong in vivo efficacy. By combining inhibitor-like rules and structure-based virtual screening, the pipeline achieved a 70% success rate in discovering diverse, nanomolar-potency reversible inhibitors and hypochlorous acid (HOCl) scavengers. Mechanistic analysis identified RL6 as a genuine MPO inhibitor and RL7 as a potent HOCl scavenger.
View Article and Find Full Text PDFJ Am Coll Emerg Physicians Open
June 2024
Division of Pulmonary, Allergy, and Critical Care University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA.
This article provides a report of a case of organ dysfunction, myonecrosis, rhabdomyolysis, multifocal ischemic cerebral infarcts, and cerebral edema after a patient's use of xylazine and fentanyl. Within the US opioid epidemic, xylazine is emerging as a troubling national sub-story. The prevalence of xylazine within illicitly manufactured opioids and the proportion of opioid-involved overdose deaths with detected xylazine are rising dramatically, the latter increasing 276% between 2019 and 2022.
View Article and Find Full Text PDFAbstractMorning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts to collaboratively examine an interesting patient presentation. The Morning Report section seeks to carry on this tradition by presenting a patient's chief concern and story, inviting the reader to develop a differential diagnosis and discover the diagnosis alongside the authors of the case.This report examines the story of a 73-year-old man who sought evaluation for 1 month of shortness of breath, bilateral lower-extremity edema, and weight gain of 14 kg.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!