This study on news coverage of highly visible company types in a Dutch daily quality newspaper (; N = 14,363), during the economic crisis (2007-2013), shows that attention to banks (and to a lesser extent also to the automobile and components industry) had a structural negative influence on media agenda diversity. The majority of the other salient company types had a significant positive impact on diversity. These results suggest that banks attracted attention at the expense of more varied, diverse coverage during the crisis. Our findings extend knowledge of agenda-building dynamics in relation to organizational news by considering characteristics of the broader media agenda. We discuss our findings in light of causes and consequences of media coverage of salient businesses.
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http://dx.doi.org/10.1177/1464884916680371 | DOI Listing |
Clin Cancer Res
January 2025
Memorial Sloan Kettering Cancer Center, New York, NY, United States.
Purpose: Recent clinical advances with the approval of antibody-drug conjugates targeting Trop-2 such as sacituzumab-govitecan and datopotomab-deruxtecan have garnered tremendous interest for their therapeutic efficacy in numerous tumor types including breast and lung cancers. ImmunoPET can stratify tumor avidity, clarifying patient eligibility for ADC therapy as well as a diagnostic companion during therapy. Slow antibody circulation requires days to reach optimal imaging timepoints.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
International Laboratory of Bioinformatics, AI and Digital Sciences Institute, Faculty of Computer Science, HSE University, Moscow, Russia.
Background: Polygenic risk score (PRS) prediction is widely used to assess the risk of diagnosis and progression of many diseases. Routinely, the weights of individual SNPs are estimated by the linear regression model that assumes independent and linear contribution of each SNP to the phenotype. However, for complex multifactorial diseases such as Alzheimer's disease, diabetes, cardiovascular disease, cancer, and others, association between individual SNPs and disease could be non-linear due to epistatic interactions.
View Article and Find Full Text PDFNPJ Parkinsons Dis
January 2025
Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder. However, current treatments only manage symptoms and lack the ability to slow or prevent disease progression. We utilized a systems genetics approach to identify potential risk genes and repurposable drugs for PD.
View Article and Find Full Text PDFJBRA Assist Reprod
January 2025
Department of Anatomical Sciences, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran.
Objective: Many cancer survivors may experience irreversible infertility due to chemotherapy treatment for childhood cancer. In this study, spermatogenesis development was evaluated following the grafting of fresh and frozen-thawed testicular tissue from neonatal mice to the epididymal fat of adult mice.
Methods: After bilateral castration of recipient mice, fresh or frozen-thawed neonatal testis tissues were grafted into the epididymal fat of the mice.
Heliyon
January 2025
Research Institute of Petroleum Exploration and Development, PetroChina, Beijing, 100083, China.
In the context of carbon neutrality, the oil and gas industry is facing increasingly stringent environmental regulatory pressures, posing severe challenges to enterprise sustainability development. This study proposes a new comprehensive calculation model to investigate the effects of low-carbon transformation and development of petrochemical enterprises in recent years. It can effectively quantify the relative efficiency of different samples in the same time interval and the efficiency change of a single sample in the time series.
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