Objective: Reintegration of cancer patients into occupational life is an important social and economic factor. Data for the "return to work" in Head and Neck Cancer (HNC) patients are sparse, especially compared with other tumor entities.
Material And Methods: In a selective literature research, original articles dealing with the theme complex "return to work in patients with HNC", between 1997 and 2018 were included and analyzed.
Results: 18 relevant articles were identified. After curative therapy, 10-52 % of previously employed patients retired from their work. The influence of the predictors tumor localization, therapy modality and gender were not consistent. However, age, socioeconomic status, therapy-related impairment (e. g. fatigue, depression) and co-morbidity were significant factors for return to work. Rehabilitation exerts a positive effect.
Conclusions: HNC patients have a high risk to retire from work. The heterogenous methods, the non-standardized points in time used for the assessments and inhomogeneous distribution in tumor localization make it difficult to compare these studies. There is an unmet need of further research in HNC patients to develop evidence-based concepts to facilitate their return to work.
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http://dx.doi.org/10.1055/a-0731-0344 | DOI Listing |
Int J Mol Sci
December 2024
Department of Hematology and Medical Oncology, Emory University, Atlanta, GA 30322, USA.
Head and neck cancer (HNC) represents a heterogeneous group of malignancies with increasing global incidence and notable mortality. Early detection is essential for improving survival rates and minimizing recurrence; however, existing diagnostic methods are often invasive and complex. There is a need for noninvasive and more effective approaches for early detection and real-time monitoring of HNC.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga Biomedical Research Institute and BIONAND Platform (IBIMA), 29010 Malaga, Spain.
Malnutrition is highly prevalent in patients with head and neck cancer, with relevant consequences in the treatment results. Multicenter observational study including 514 patients diagnosed with HNC. The morphofunctional assessment was carried out during the first 2 weeks of radiotherapy treatment.
View Article and Find Full Text PDFCancers (Basel)
December 2024
UofL Health-Brown Cancer Center, Department of Medicine, University of Louisville, Louisville, KY 40202, USA.
Background: Over the past decade, saliva-based liquid biopsies have emerged as promising tools for the early diagnosis, prognosis, and monitoring of cancer, particularly in high-risk populations. However, challenges persist because of low concentrations and variable modifications of biomarkers linked to tumor development when compared to normal salivary components.
Methods: This study explores the application of differential scanning calorimetry (DSC)-based thermal liquid biopsy (TLB) for analyzing saliva and blood plasma samples from head and neck cancer (HNC) patients.
Int J Surg Oncol
January 2025
Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brazil.
As head and neck cancer (HNC) affects regions directly related to the digestive tract, it is consistently associated with nutritional impact symptoms (NISs), which further reduce food intake and affect nutritional status. Early identification of patients with NIS can assist therapy. This is a cross-sectional study with HNC patients from a cancer reference hospital.
View Article and Find Full Text PDFLaryngoscope
January 2025
Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Objectives: To evaluate the impact of delayed postoperative radiotherapy (PORT) on overall survival (OS) in patients with head and neck cancers (HNC).
Data Sources: A systematic review and meta-analysis were conducted by searching MEDLINE, Embase, CENTRAL, Web of Science, and CINAHL databases.
Review Methods: Studies assessing the impact of delayed PORT in adult HNC patients were included.
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