Purpose: To compare uncorrected distance visual acuity (UDVA) and best-corrected distance visual acuity (CDVA) between patients with keratoconus (KC) and matched patients with regular myopic astigmatism.
Methods: This retrospective study included consecutive patients diagnosed with KC between 2008 and 2013 at Care-Vision Laser Centers, Tel-Aviv, Israel, and matched patients with regular myopic astigmatism. Data included were central corneal thickness (CCT), spherical equivalent (SE), cylinder (CYL), mean keratometric power, maximum keratometric power (K), UDVA, CDVA, and defocus equivalent (DEQ).
Results: The KC group included 734 patients with a mean age of 33.8 ± 9.5 years. The matched, control group included 1462 patients with a mean age of 33.2 ± 9.7 years (p = 0.14). The mean SE and CYL of the KC group were - 3.34 ± 3.29D and - 3.01 ± 1.99D, respectively, compared to - 3.34 ± 2.92D (p = 0.98) and - 2.97 ± 1.35 (p = 0.58). Mean K (46.8 ± 3.3D versus 44.0 ± 1.8D, p < 0.0001) and K (48.4 ± 4.0D versus 45.3 ± 2.0D, p < 0.0001) were statically significant higher in the KC group. CCT was significantly thinner in the KC group (444 ± 49 versus 527 ± 40 μm, p < 0.0001). The KC group had a better UDVA than the non-KC group (1.10 ± 0.68 versus 1.22 ± 0.64 logMAR, p < 0.0001). CDVA was significantly lower in the KC group (p < 0.001).
Conclusions: For defocus equivalents above 6D, the KC group had better UDVA than the non-KC group in spite of worse CDVA.
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http://dx.doi.org/10.1007/s00417-018-4188-1 | DOI Listing |
Eye (Lond)
January 2025
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Purpose: To utilize optical coherence tomography (OCT) and SS-OCT angiography (SS-OCTA) for quantifying morphological changes seen in eyes with recalcitrant neovascular age-related macular degeneration (nAMD) transitioned to intravitreal faricimab injections during the manufacturer's recommended induction phase of treatment.
Methods: Fifty-four treatment-recalcitrant patients (60 eyes) were recruited. OCT and SS-OCTA images were obtained at 0 and 3 months.
Eye (Lond)
January 2025
Maidstone Hospital Eye Department, Hermitage Lane, Maidstone, UK.
Background And Objectives: Faricimab, a bispecific antibody targeting VEGF-A and angiopoietin-2, has shown promise in treating neovascular age-related macular degeneration (nAMD). This study evaluates 1-year outcomes of faricimab in treatment-experienced nAMD patients.
Methods: This single-centre retrospective cohort study included patients previously treated for nAMD who switched to faricimab between November 2022 and March 2024.
Sci Rep
January 2025
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
People with amblyopia show deficits in global motion perception, especially at slow speeds. These observers are also known to have unstable fixation when viewing stationary fixation targets, relative to healthy controls. It is possible that poor fixation stability during motion viewing interferes with the fidelity of the input to motion-sensitive neurons in visual cortex.
View Article and Find Full Text PDFSurv Ophthalmol
January 2025
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China; Key Lab of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address:
Because of its benign nature and rarity, circumscribed choroidal hemangioma (CCH) often receives limited attention, leading to a high rate of misdiagnosis and a lack of standardized treatment protocols. We provide a thorough clarification of the demographics, clinical features, diagnosis, management, and prognosis of CCH. We conducted a systematic search of the PubMed, EMBASE, and Ovid databases up to December, 2023, to identify relevant studies.
View Article and Find Full Text PDFPharmaceutics
January 2025
Centre for Public Health, Institute of Clinical Sciences, School of Medicine, Queen's University Belfast, Belfast BT7 1NN, UK.
Background/objectives: The visual acuity (VA) outcomes after the first and second years of anti-vascular endothelial growth factor (anti-VEGF) treatment in patients with diabetic macular oedema (DMO) were evaluated, and the factors associated with treatment success were investigated.
Methods: Using Medisoft electronic medical records (UK), this retrospective cohort study analysed VA outcomes, changes, and determinants in DMO patients at year 1 and year 2 after initial anti-VEGF injection. Descriptive analysis examined baseline demographics and clinical characteristics, while regression models were used to assess associations between these factors and changes in VA.
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