Macrophage activation syndrome (MAS) is a rare and potentially fatal condition characterized by excessive activation and uncontrolled proliferation of T lymphocytes and macrophages, leading to overwhelming systemic inflammation and cytokine release. MAS has been reported with viral infections, autoimmune disorders, malignancies, and medications. We describe a case of a patient with axial spondyloarthritis (axSpA) treated with adalimumab, who presented with MAS.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087649PMC
http://dx.doi.org/10.1007/s10067-018-4387-5DOI Listing

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