[First report in Chile of a clinical isolate of Escherichia coli resistant to colistin harbouring the mcr-1 gene].

Rev Chilena Infectol

Departamento de Laboratorios Clínicos, Escuela de Medicina, Pontificia Universidad Católica de Chile, Chile.

Published: August 2018

AI Article Synopsis

  • Researchers identified the mcr-1 gene, which is linked to colistin resistance, in clinical samples.
  • They used PCR and sequencing techniques to screen 13 colistin-resistant isolates and found the gene in one E. coli sample.
  • This finding marks the first documented case of the mcr-1 gene being present in Chile.

Article Abstract

Recently it was described the plasmidial gene mcr-1 associated with colistin resistance. We screened by PCR and sequencing for gene mcr-1 in thirteen clinical isolates resistant to colistin. We observed amplification in one E. coli. To our knowledge, this is the first report of the presence of mcr-1 gene in Chile.

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Source
http://dx.doi.org/10.4067/s0716-10182018000400453DOI Listing

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