Carboplatin-induced Kounis syndrome.

J Cardiol Cases

Cardiology Department, Policlinico San Pietro, Via Forlanini 15, 24036 Ponte S. Pietro (BERGAMO), Italy.

Published: August 2011

A 50-year-old man in chemotherapy for an advanced lung adenocarcinoma presented with chest pain and cutaneous rash during carboplatin infusion with electrocardiographic (ECG) evidence of an inferior lesion wave. The administration of steroids and nitrates promptly resulted in clinical and ECG normalization, without enzymatic dismission. This reaction was considered compatible with allergic coronary vasospasm (also known as Kounis syndrome), a rare but possible complication of chemotherapy. In these cases prompt diagnosis and a correct approach can avoid useless invasive interventions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265130PMC
http://dx.doi.org/10.1016/j.jccase.2011.04.004DOI Listing

Publication Analysis

Top Keywords

kounis syndrome
8
carboplatin-induced kounis
4
syndrome 50-year-old
4
50-year-old man
4
man chemotherapy
4
chemotherapy advanced
4
advanced lung
4
lung adenocarcinoma
4
adenocarcinoma presented
4
presented chest
4

Similar Publications

Kounis syndrome also known as allergic myocardial infarction, represents the simultaneous occurrence of acute coronary syndromes with allergic or hypersensitivity reactions. We present a case of a 58-years-old male who developed anaphylaxis following a leech bite, leading to myocardial infarction despite the absence of prior allergic history. He was entubated and cardiopulmonary resusciation had been performed for 10 minutes.

View Article and Find Full Text PDF

Kounis Syndrome Following a Wasp Sting.

Am J Forensic Med Pathol

January 2025

From the Department of Forensic Medicine, University of Pretoria, Prinshof Campus, Pretoria, South Africa.

View Article and Find Full Text PDF

To study a case of Kounis syndrome (KS) type II, characterized by allergy, myocardial infarction, and ventricular fibrillation. A patient diagnosed with KS type II was admitted to Yangpu Hospital, School of Medicine, Tongji University in 2021. After systemic treatment, routine investigations, including blood tests, electrocardiography (ECG), and biochemical and coagulation analyses, were performed.

View Article and Find Full Text PDF

Kounis Syndrome Following Moxifloxacin and Deflazacort Administration.

Eur J Case Rep Intern Med

December 2024

Emergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Lugano, Lugano, Switzerland.

Unlabelled: Kounis syndrome (KS), characterized by the simultaneous occurrence of acute coronary syndrome (ACS) and allergic reactions, can be triggered by a range of factors and drugs. We report on the case of a patient who arrived at our emergency department (ED) with symptoms of an allergic reaction after taking moxifloxacin and deflazacort orally. In the ED, the patient experienced a 5-minute episode of oppressive chest pain.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!