In order to analyze the spread of avian influenza A (H7N9), we construct an avian influenza transmission model from poultry (including poultry farm, backyard poultry farm, live-poultry wholesale market, and wet market) to human according to poultry transport network. We obtain the threshold value for the prevalence of avian influenza A (H7N9) and also give the existence and number of the boundary equilibria and endemic equilibria in different conditions. We can see that poultry transport network plays an important role in controlling avian influenza A (H7N9). Finally, numerical simulations are presented to illustrate the effects of poultry in different places on avian influenza. In order to reduce human infections in China, our results suggest that closing the retail live-poultry market or preventing the poultry of backyard poultry farm into the live-poultry market is feasible in a suitable condition.
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http://dx.doi.org/10.1155/2018/7383170 | DOI Listing |
Poult Sci
January 2025
Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, PR China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, PR China; Jiangsu Key Laboratory of Zoonoses, Yangzhou University, Yangzhou, PR China. Electronic address:
H7N9 avian influenza virus (AIV) first emerged in February 2013 in China, and early isolates were all low pathogenic (LP). After circulation for a few years in live poultry markets of China, LP H7N9 AIVs evolved into a highly pathogenic (HP) form in late 2016. Deduced amino acid sequence analysis of hemagglutinin (HA) gene revealed that all HP H7N9 AIVs have obtained four-amino-acid insertion at position 339-342 (H7 numbering), making the cleavage site from a monobasic motif (LP AIVs) to a polybasic form (HP AIVs).
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January 2025
Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, 250 Kuo Kuang Road, Taichung 40227, Taiwan.
The outbreaks of several epidemics caused by pathogenic avian viruses pose significant threats to the poultry industry [...
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January 2025
Département de Virologie, Institut Pasteur de Dakar, Dakar BP 220, Senegal.
Despite extensive experience with influenza surveillance in humans in Senegal, there is limited knowledge about the actual situation and genetic diversity of avian influenza viruses (AIVs) circulating in the country, hindering control measures and pandemic risk assessment. Therefore, as part of the "One Health" approach to influenza surveillance, we conducted active AIV surveillance in two live bird markets (LBMs) in Dakar to better understand the dynamics and diversity of influenza viruses in Senegal, obtain genetic profiles of circulating AIVs, and assess the risk of emergence of novel strains and their transmission to humans. Cloacal swabs from poultry and environmental samples collected weekly from the two LBMs were screened by RT-qPCR for H5, H7, and H9 AIVs.
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December 2024
Department of Microbiology and Immunology, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.
Influenza A virus (IAV) remains a pandemic threat. Particularly, the evolution and increased interspecies and intercontinental transmission of avian IAV H5N1 subtype highlight the importance of continuously studying the IAV and identifying the determinants of its pathogenesis. Host innate antiviral response is the first line of defense against IAV infection, and the transcription factor, the signal transducer and activator of transcription 3 (STAT3), has emerged as a critical component of this response.
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December 2024
Sovon Dutch Centre for Field Ornithology, 6525 ED Nijmegen, The Netherlands.
Highly pathogenic avian influenza (HPAI) epizootics have caused repeated mass mortality events among wild birds. The effect of the infection is potentially detrimental for a variety of bird species, including the Peregrine Falcon (). The numbers of wintering and breeding Peregrine Falcons in the Netherlands have recently declined.
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