Primary clear cell adenocarcinoma of the pancreas: a case report and literature update.

Onco Targets Ther

Department of Hepatobiliary Surgery, Weihai Central Hospital, Weihai 264400, Shandong Province, People's Republic of China,

Published: November 2018

AI Article Synopsis

  • Primary clear cell carcinoma of the pancreas is a very rare type of tumor, highlighted in a case study of a 64-year-old male.
  • The patient had surgery to remove the tumor, which was found in the distal body and tail of the pancreas, and its cells showed distinct characteristics under microscopic examination.
  • The tumor's analysis revealed specific reactions to certain antibodies, leading to the diagnosis of primary clear cell carcinoma, marking it as a unique case in existing medical literature.

Article Abstract

Primary clear cell carcinoma of pancreas is extremely rare. We present a case of a 64-year-old male with a mass in the distal body and tail of the pancreas. He underwent a distal pancreatectomy. The histopathology of tumor cells showed features with abundant clear cytoplasm and prominent cell boundaries. Immunohistochemical analysis of neoplastic cells showed reactions to antibodies against cytokeratin-7 and showed no reactions to antibodies against hepatocyte nuclear factor-1β, carbonic anhydrase 9, synaptophysin, and chromogranin A. The patient was subsequently diagnosed with a primary clear cell carcinoma of the pancreas. This is the first time we have encountered it. We report this rare case and update the current literature of this tumor.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247962PMC
http://dx.doi.org/10.2147/OTT.S183054DOI Listing

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