Roth spots are petechiae of the retina with a white or pale center that corresponds to a bundle of cotton wool or a multinuclear leukocyte aggregate. Often considered a sign of bacterial endocarditis, they are an unspecific symptom, usually more commonly seen in patients with hematopoietic system diseases. A 56-year-old patient reported to the hospital due to sudden visual impairment. The fundoscopy revealed Roth spots in both eyes that aroused the suspicion of infective endocarditis. After confirming the condition at the Department of Cardiology and the implementation of the treatment, there was a significant improvement in visual acuity, including the resolution of retinal changes. The presented case presents an accurate, still rare ophthalmic diagnosis of infective endocarditis.

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