Integration of unusual domains in plant immune receptors is a widespread mechanism of NLR diversification enabling specific pathogen detection.
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http://dx.doi.org/10.1104/pp.18.01134 | DOI Listing |
J Integr Plant Biol
January 2025
Department of Plant Pathology, Nanjing Agricultural University, Nanjing, 210095, China.
Plant viruses cause substantial agricultural devastation and economic losses worldwide. Plant nucleotide-binding domain leucine-rich repeat receptors (NLRs) play a pivotal role in detecting viral infection and activating robust immune responses. Recent advances, including the elucidation of the interaction mechanisms between NLRs and pathogen effectors, the discovery of helper NLRs, and the resolution of the ZAR1 resistosome structure, have significantly deepened our understanding of NLR-mediated immune responses, marking a new era in NLR research.
View Article and Find Full Text PDFSci Bull (Beijing)
December 2024
CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China; University of the Chinese Academy of Sciences, Beijing 100039, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address:
Nucleotide-binding leucine-rich repeat (NLR) receptors mediate pathogen effector-triggered immunity (ETI) in plants, and a subclass of NLRs are hypothesized to function at the plasma membrane (PM). However, how NLR traffic and PM delivery are regulated during immune responses remains largely unknown. The rice NLR PigmR confers broad-spectrum resistance to the blast fungus Magnaporthe oryzae.
View Article and Find Full Text PDFPlant Mol Biol
December 2024
Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, 210014, China.
Dioscorea alata, a key tuber crop for global food security, is threatened by anthracnose disease caused by Colletotrichum gloeosporioides. However, identification of functional resistance genes against C. gloeosporioides in D.
View Article and Find Full Text PDFAdv Sci (Weinh)
December 2024
International Genome Center, Jiangsu University, Zhenjiang, 212013, China.
Unlike animals, plants are unable to move and lack specialized immune cells and circulating antibodies. As a result, they are always threatened by a large number of microbial pathogens and harmful pests that can significantly reduce crop yield worldwide. Therefore, the development of new strategies to control them is essential to mitigate the increasing risk of crops lost to plant diseases.
View Article and Find Full Text PDFPlants (Basel)
November 2024
State Key Laboratory of Rice Biology & Ministry of Agriculture Key Laboratory of Agricultural Entomology, Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Institute of Insect Sciences, Zhejiang University, Hangzhou 310058, China.
Plant nucleotide-binding leucine-rich repeat immune receptor genes (NLRs) play an important role in plant defenses against pathogens, pathogenic nematodes, and piercing-sucking herbivores. However, little is known about their functions in plant defenses against chewing herbivores. Here, we identified a plasma membrane-localized coiled-coil-type NLR protein, OsPik-2-like, whose transcript levels were induced by the infestation of rice leaf folder (LF, ) larvae, and by treatment with mechanical wounding.
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